Biomaterial Database

Apoplectic headache and oculomotor nerve palsy: an unusual presentation of multiple sclerosis. 1990

B S Galer, and R B Lipton, and S Weinstein, and L Bello, and S Solomon

Department of Neurology, Albert Einstein College of Medicine, Bronx, NY.

A patient with a history of facial myokymia presented with apoplectic headache and a 3rd nerve palsy. Initial CT, lumbar puncture, and cerebral angiogram were unremarkable, but subsequent CSF examination revealed oligoclonal bands. MRI displayed over 30 white matter lesions. This case demonstrates that multiple sclerosis may present with severe headache and a 3rd nerve palsy, simulating the clinical picture of a posterior communicating artery aneurysm.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009103	Multiple Sclerosis	An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)	MS (Multiple Sclerosis),Multiple Sclerosis, Acute Fulminating,Sclerosis, Disseminated,Disseminated Sclerosis,Sclerosis, Multiple
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D014653	Vascular Headaches	Secondary headache disorders attributed to a variety of cranial or cervical vascular disorders, such as BRAIN ISCHEMIA; INTRACRANIAL HEMORRHAGES; and CENTRAL NERVOUS SYSTEM VASCULAR MALFORMATIONS.	Cephalgia, Vascular,Headache, Vascular,Vascular Headache,Cephalgias, Vascular,Headaches, Vascular,Vascular Cephalgia,Vascular Cephalgias
D015840	Oculomotor Nerve Diseases	Diseases of the oculomotor nerve or nucleus that result in weakness or paralysis of the superior rectus, inferior rectus, medial rectus, inferior oblique, or levator palpebrae muscles, or impaired parasympathetic innervation to the pupil. With a complete oculomotor palsy, the eyelid will be paralyzed, the eye will be in an abducted and inferior position, and the pupil will be markedly dilated. Commonly associated conditions include neoplasms, CRANIOCEREBRAL TRAUMA, ischemia (especially in association with DIABETES MELLITUS), and aneurysmal compression. (From Adams et al., Principles of Neurology, 6th ed, p270)	Cranial Nerve III Diseases,Third-Nerve Palsy,Oculomotor Nerve Disorders,Oculomotor Nerve Palsy,Oculomotor Nerve Paralysis,Oculomotor Neuropathy,Partial Third-Nerve Palsy,Third Cranial Nerve Diseases,Third-Nerve Paralysis,Total Third-Nerve Palsy,Nerve Disease, Oculomotor,Nerve Disorder, Oculomotor,Nerve Palsy, Oculomotor,Nerve Paralysis, Oculomotor,Neuropathy, Oculomotor,Oculomotor Nerve Disease,Oculomotor Nerve Disorder,Oculomotor Nerve Palsies,Oculomotor Nerve Paralyses,Oculomotor Neuropathies,Palsy, Oculomotor Nerve,Palsy, Partial Third-Nerve,Palsy, Third-Nerve,Palsy, Total Third-Nerve,Paralysis, Oculomotor Nerve,Paralysis, Third-Nerve,Partial Third Nerve Palsy,Partial Third-Nerve Palsies,Third Nerve Palsy,Third Nerve Paralysis,Third-Nerve Palsies,Third-Nerve Palsies, Partial,Third-Nerve Palsy, Partial,Third-Nerve Palsy, Total,Third-Nerve Paralyses,Total Third Nerve Palsy,Total Third-Nerve Palsies