BIOMAT Database Logo BIOMAT Database Logo

Effect of anoxia on spontaneous discharges of the cochlear single unit in guinea pigs. 1990

H Kitano, and M Kitahara, and M Suzuki
Department of Otolaryngology, Shiga University of Medical Science, Otsu, Japan.

The present experiment examined the effect of anoxia on the spontaneous discharges of cochlear single units in guinea pigs; several additional animals were tested for the combined effect of anoxia and sodium salicylate. Following the induction of anoxia, initial increases in the number of spontaneous discharges were seen in 19 of the 34 cochlear single units tested. Neurons showing high frequencies during normal respiration tended toward increased rates of discharge during anoxia. In the 5 animals pretreated with sodium salicylate, remarkable increases in the spike rates were noted following the induction of anoxia.

UI MeSH Term Description Entries
D008564 Membrane Potentials The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization). Resting Potentials,Transmembrane Potentials,Delta Psi,Resting Membrane Potential,Transmembrane Electrical Potential Difference,Transmembrane Potential Difference,Difference, Transmembrane Potential,Differences, Transmembrane Potential,Membrane Potential,Membrane Potential, Resting,Membrane Potentials, Resting,Potential Difference, Transmembrane,Potential Differences, Transmembrane,Potential, Membrane,Potential, Resting,Potential, Transmembrane,Potentials, Membrane,Potentials, Resting,Potentials, Transmembrane,Resting Membrane Potentials,Resting Potential,Transmembrane Potential,Transmembrane Potential Differences
D003051 Cochlea The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH. Cochleas
D004594 Electrophysiology The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.
D006168 Guinea Pigs A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research. Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000860 Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms. Anoxia,Oxygen Deficiency,Anoxemia,Deficiency, Oxygen,Hypoxemia,Deficiencies, Oxygen,Oxygen Deficiencies
D012980 Sodium Salicylate A non-steroidal anti-inflammatory agent that is less effective than equal doses of ASPIRIN in relieving pain and reducing fever. However, individuals who are hypersensitive to ASPIRIN may tolerate sodium salicylate. In general, this salicylate produces the same adverse reactions as ASPIRIN, but there is less occult gastrointestinal bleeding. (From AMA Drug Evaluations Annual, 1992, p120) Salicylate, Sodium

Related Publications

H Kitano, and M Kitahara, and M Suzuki
Spontaneous continuous motor unit single discharges.
March 2020, Muscle & nerve,
H Kitano, and M Kitahara, and M Suzuki
Effect of electro-acupuncture of "Neiguan" on spontaneous discharges of single unit in amygdaloid nucleus in rabbits.
June 1989, Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan,
H Kitano, and M Kitahara, and M Suzuki
[Effects of capsaicin on spontaneous unit discharges in amygdala single neurons of cats].
January 1987, Nihon yakurigaku zasshi. Folia pharmacologica Japonica,
H Kitano, and M Kitahara, and M Suzuki
Effect of carbon dioxide on cochlear blood flow in guinea pigs.
January 2000, Acta oto-laryngologica,
H Kitano, and M Kitahara, and M Suzuki
[Effect of anisodamine on cochlear blood flow in living guinea pigs].
January 1992, Zhonghua er bi yan hou ke za zhi,
H Kitano, and M Kitahara, and M Suzuki
Single-unit discharges in the dorsolateral thalamus of behaving cats: spontaneous activity.
July 1979, Experimental neurology,
H Kitano, and M Kitahara, and M Suzuki
Effects of anoxia on the cochlear summating potential in the guinea pig.
January 1992, European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery,
H Kitano, and M Kitahara, and M Suzuki
The effect of systemic administration of desmopressin on cochlear function in guinea pigs.
July 2013, Acta oto-laryngologica,
H Kitano, and M Kitahara, and M Suzuki
Effect of ouabain on cochlear potentials and endolymph composition in guinea pigs.
March 1970, Acta oto-laryngologica,
H Kitano, and M Kitahara, and M Suzuki
Effect of focal cochlear vascular lesion on endocochlear potential in guinea pigs.
September 1995, Hearing research,
Copied contents to your clipboard!