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Fc receptor mediated immune complex clearance function was measured in patients with systemic lupus erythematosus. Autologous erythrocytes were sensitized by human IgG anti-Rh(D) and used as immune complex model. An impaired Fc receptor function was demonstrable in 20 of 25 investigated patients. We have found a significant correlation between the seriousness of the defect and the step of the immunologic activity of the patients, but not between the impaired Fc receptor function and clinical activity and renal manifestation in our SLE patients. Further studies are necessary to determine the relevance of this phenomenon and to clear the possibility of therapeutical influence.
P Kästner, and
H Franke, and
P Kleinert, and
C Günther, and
K Malberg, and
M Löbnitz
October 1982,
Annals of internal medicine,
P Kästner, and
H Franke, and
P Kleinert, and
C Günther, and
K Malberg, and
M Löbnitz
February 1983,
Clinical and experimental immunology,
P Kästner, and
H Franke, and
P Kleinert, and
C Günther, and
K Malberg, and
M Löbnitz
June 1989,
Arthritis and rheumatism,
P Kästner, and
H Franke, and
P Kleinert, and
C Günther, and
K Malberg, and
M Löbnitz
November 1984,
Journal of immunology (Baltimore, Md. : 1950),
P Kästner, and
H Franke, and
P Kleinert, and
C Günther, and
K Malberg, and
M Löbnitz
January 1982,
The Journal of rheumatology,
P Kästner, and
H Franke, and
P Kleinert, and
C Günther, and
K Malberg, and
M Löbnitz
July 1986,
Journal of immunology (Baltimore, Md. : 1950),
P Kästner, and
H Franke, and
P Kleinert, and
C Günther, and
K Malberg, and
M Löbnitz
March 1979,
The New England journal of medicine,
P Kästner, and
H Franke, and
P Kleinert, and
C Günther, and
K Malberg, and
M Löbnitz
August 1994,
Annals of hematology,
P Kästner, and
H Franke, and
P Kleinert, and
C Günther, and
K Malberg, and
M Löbnitz
February 1977,
Archives of dermatology,
P Kästner, and
H Franke, and
P Kleinert, and
C Günther, and
K Malberg, and
M Löbnitz
June 1987,
The Journal of rheumatology,
