Biomaterial Database

Adherence to antiretroviral therapy and its associated factors among people living with HIV/AIDS in Addis Ababa, Ethiopia. 2012

Zuriyash Mengistu, and Amsale Chere

Department of Nursing, Faculty of Medicine, Addis Ababa University.

BACKGROUND HIV/AIDS became a chronic illness since the introduction of Anti-Retroviral-Therapy which needs ongoing assessment for adherence to prevent treatment failure. OBJECTIVE The objective of this study was to assess antiretroviral therapy adherence and its associated factors. METHODS A cross-sectional quantitative study was conducted on 420 People Living With HIV/AIDS (PLWHA) who were attending Anti-Retroviral-Therapy clinic at Tikur Anbessa, Zewditu and St Paul's Hospitals from March to April 2009. Systematic random sampling technique was used to select the participants from their document. Then Data were collected, checked, categorized, coded and analyzed using SPSS 15.0 statistical package. RESULTS From the total 420 respondents, 244 (58.1%) were women. Among the respondents, 308 (73.3%) had adhered to Anti-Retroviral-Therapy (ART). Respondents who had good relationship with health care provider had 3.15 times more likely to adhere to ART compared to those who had poor relationship. Those who stated stigma and discrimination as a major problem were 81% less likely to adhere to ART compared to those who stated stigma and discrimination not to be a problem at all. CONCLUSIONS The findings of the study indicate that ART adherence rate to be low. The study also showed that Stigma and discrimination, and poor relationship with health care provider to be associated with low adherence. Based on the finding, keep away from stigmatization and discrimination, and enhancing good relationship need to be given attention for improving ART adherence.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010817	Physician-Patient Relations	The interactions between physician and patient.	Doctor-Patient Relations,Doctor Patient Relations,Physician Patient Relations,Physician Patient Relationship,Doctor Patient Relation,Doctor-Patient Relation,Physician Patient Relation,Physician Patient Relationships,Physician-Patient Relation,Relation, Doctor Patient,Relation, Doctor-Patient,Relation, Physician Patient,Relation, Physician-Patient,Relations, Doctor Patient,Relations, Doctor-Patient,Relations, Physician Patient,Relations, Physician-Patient,Relationship, Physician Patient,Relationships, Physician Patient
D011287	Prejudice	A preconceived judgment made without factual basis.	Anti-Semitism,Islamophobia,Anti Semitism,Anti-Semitisms,Islamophobias,Prejudices
D012067	Religion	A set of beliefs concerning the nature, cause, and purpose of the universe, especially when considered as the creation of a superhuman agency. It usually involves devotional and ritual observances and often a moral code for the conduct of human affairs. (Random House Collegiate Dictionary, rev. ed.)	Prayer,Religious Beliefs,Religious Ethics,Beliefs, Religious,Ethic, Religious,Prayers,Religions,Religious Belief
D005002	Ethiopia	An independent state in eastern Africa. Ethiopia is located in the Horn of Africa and is bordered on the north and northeast by Eritrea, on the east by Djibouti and Somalia, on the south by Kenya, and on the west and southwest by Sudan. Its capital is Addis Ababa.	Federal Democratic Republic of Ethiopia
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000163	Acquired Immunodeficiency Syndrome	An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.	AIDS,Immunodeficiency Syndrome, Acquired,Immunologic Deficiency Syndrome, Acquired,Acquired Immune Deficiency Syndrome,Acquired Immuno-Deficiency Syndrome,Acquired Immuno Deficiency Syndrome,Acquired Immuno-Deficiency Syndromes,Acquired Immunodeficiency Syndromes,Immuno-Deficiency Syndrome, Acquired,Immuno-Deficiency Syndromes, Acquired,Immunodeficiency Syndromes, Acquired,Syndrome, Acquired Immuno-Deficiency,Syndrome, Acquired Immunodeficiency,Syndromes, Acquired Immuno-Deficiency,Syndromes, Acquired Immunodeficiency
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults