Ocular vestibular evoked myogenic potentials in response to air-conducted sound and bone-conducted vibration in vestibular schwannoma. 2013

Makoto Kinoshita, and Shinichi Iwasaki, and Chisato Fujimoto, and Aki Inoue, and Naoya Egami, and Yasuhiro Chihara, and Munetaka Ushio, and Tatsuya Yamasoba
Department of Otolaryngology and Head and Neck Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan.

OBJECTIVE To clarify the origin and pathways of ocular vestibular evoked myogenic potentials (oVEMPs) to air-conducted sound (ACS), we compared the results of oVEMPs with ACS, with oVEMPs with bone-conducted vibration (BCV), cervical VEMPs (cVEMPs) with ACS, and the caloric test in patients with unilateral vestibular schwannoma (VS). METHODS Retrospective review. METHODS Tertiary referral center. METHODS Forty-five patients with untreated unilateral VS. METHODS Each patient underwent vestibular tests, including oVEMPs to ACS, oVEMPs to BCV, cVEMPs to ACS, and caloric tests. The correlations among these tests were evaluated. RESULTS Of the 45 patients recruited, 28 patients (63%) showed reduced or absent oVEMPs to ACS solely on the affected side. There were no significant differences in abnormal response ratios among oVEMPs to ACS, oVEMPs to BCV, cVEMPs to ACS, or the caloric test. The results of oVEMPs to ACS had a significant correlation with those of oVEMPs to BCV and the caloric test (p < 0.05) but not with those of cVEMPs to ACS (p > 0.05). CONCLUSIONS These findings support the hypothesis that oVEMP in response to ACS are predominantly mediated by the superior vestibular nerve and probably reflect the function of the utricle.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009464 Neuroma, Acoustic A benign SCHWANNOMA of the eighth cranial nerve (VESTIBULOCOCHLEAR NERVE), mostly arising from the vestibular branch (VESTIBULAR NERVE) during the fifth or sixth decade of life. Clinical manifestations include HEARING LOSS; HEADACHE; VERTIGO; TINNITUS; and FACIAL PAIN. Bilateral acoustic neuromas are associated with NEUROFIBROMATOSIS 2. (From Adams et al., Principles of Neurology, 6th ed, p673) Acoustic Neuroma,Melanocytic Vestibular Schwannoma,Schwannoma, Acoustic,Schwannoma, Vestibular,Acoustic Neuroma, Cerebellopontine Angle,Acoustic Tumor,Angle Tumor,Cerebellopontine Angle Acoustic Neuroma,Cerebellopontine Angle Tumor,Neurilemmoma, Acoustic,Neurilemoma, Acoustic,Neurinoma of the Acoustic Nerve,Neurinoma, Acoustic,Neuroma, Acoustic, Unilateral,Vestibular Schwannoma,Acoustic Neurilemmoma,Acoustic Neurilemmomas,Acoustic Neurilemoma,Acoustic Neurilemomas,Acoustic Neurinoma,Acoustic Neurinomas,Acoustic Neuromas,Acoustic Schwannoma,Acoustic Schwannomas,Acoustic Tumors,Angle Tumor, Cerebellopontine,Angle Tumors,Angle Tumors, Cerebellopontine,Cerebellopontine Angle Tumors,Melanocytic Vestibular Schwannomas,Neurilemmomas, Acoustic,Neurilemomas, Acoustic,Neurinomas, Acoustic,Neuromas, Acoustic,Schwannoma, Melanocytic Vestibular,Schwannomas, Acoustic,Schwannomas, Melanocytic Vestibular,Schwannomas, Vestibular,Tumor, Acoustic,Tumor, Angle,Tumor, Cerebellopontine Angle,Tumors, Acoustic,Tumors, Angle,Tumors, Cerebellopontine Angle,Vestibular Schwannoma, Melanocytic,Vestibular Schwannomas,Vestibular Schwannomas, Melanocytic
D012027 Reflex, Vestibulo-Ocular A reflex wherein impulses are conveyed from the cupulas of the SEMICIRCULAR CANALS and from the OTOLITHIC MEMBRANE of the SACCULE AND UTRICLE via the VESTIBULAR NUCLEI of the BRAIN STEM and the median longitudinal fasciculus to the OCULOMOTOR NERVE nuclei. It functions to maintain a stable retinal image during head rotation by generating appropriate compensatory EYE MOVEMENTS. Vestibulo-Ocular Reflex,Reflex, Vestibuloocular,Reflexes, Vestibo-Ocular,Reflexes, Vestibuloocular,Reflex, Vestibulo Ocular,Reflexes, Vestibo Ocular,Vestibo-Ocular Reflexes,Vestibulo Ocular Reflex,Vestibuloocular Reflex,Vestibuloocular Reflexes
D001844 Bone Conduction Transmission of sound waves through vibration of bones in the SKULL to the inner ear (COCHLEA). By using bone conduction stimulation and by bypassing any OUTER EAR or MIDDLE EAR abnormalities, hearing thresholds of the cochlea can be determined. Bone conduction hearing differs from normal hearing which is based on air conduction stimulation via the EAR CANAL and the TYMPANIC MEMBRANE. Bone Conduction Hearing,Conduction Hearing, Bone,Conduction, Bone,Hearing, Bone Conduction
D002150 Caloric Tests Elicitation of a rotatory nystagmus by stimulating the semicircular canals with water or air which is above or below body temperature. In warm caloric stimulation a rotatory nystagmus is developed toward the side of the stimulated ear; in cold, away from the stimulated side. Absence of nystagmus indicates the labyrinth is not functioning. Barany Test,Barany's Test,Baranys Test,Caloric Test,Test, Barany,Test, Barany's,Test, Caloric,Tests, Caloric
D004424 Ear Canal The narrow passage way that conducts the sound collected by the EAR AURICLE to the TYMPANIC MEMBRANE. Auditory Canal, External,External Acoustic Canal,External Acoustic Meatus,External Auditory Canal,External Ear Canal,Acoustic Canal, External,Acoustic Canals, External,Acoustic Meatus, External,Auditory Canals, External,Canal, Ear,Canal, External Ear,Canals, Ear,Canals, External Ear,Ear Canal, External,Ear Canals,Ear Canals, External,External Acoustic Canals,External Auditory Canals,External Ear Canals
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000161 Acoustic Stimulation Use of sound to elicit a response in the nervous system. Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory

Related Publications

Makoto Kinoshita, and Shinichi Iwasaki, and Chisato Fujimoto, and Aki Inoue, and Naoya Egami, and Yasuhiro Chihara, and Munetaka Ushio, and Tatsuya Yamasoba
November 2012, Experimental brain research,
Makoto Kinoshita, and Shinichi Iwasaki, and Chisato Fujimoto, and Aki Inoue, and Naoya Egami, and Yasuhiro Chihara, and Munetaka Ushio, and Tatsuya Yamasoba
January 2010, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,
Makoto Kinoshita, and Shinichi Iwasaki, and Chisato Fujimoto, and Aki Inoue, and Naoya Egami, and Yasuhiro Chihara, and Munetaka Ushio, and Tatsuya Yamasoba
March 2015, Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
Makoto Kinoshita, and Shinichi Iwasaki, and Chisato Fujimoto, and Aki Inoue, and Naoya Egami, and Yasuhiro Chihara, and Munetaka Ushio, and Tatsuya Yamasoba
February 2007, Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
Makoto Kinoshita, and Shinichi Iwasaki, and Chisato Fujimoto, and Aki Inoue, and Naoya Egami, and Yasuhiro Chihara, and Munetaka Ushio, and Tatsuya Yamasoba
October 2011, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,
Makoto Kinoshita, and Shinichi Iwasaki, and Chisato Fujimoto, and Aki Inoue, and Naoya Egami, and Yasuhiro Chihara, and Munetaka Ushio, and Tatsuya Yamasoba
October 2018, Acta oto-laryngologica,
Makoto Kinoshita, and Shinichi Iwasaki, and Chisato Fujimoto, and Aki Inoue, and Naoya Egami, and Yasuhiro Chihara, and Munetaka Ushio, and Tatsuya Yamasoba
September 2012, Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
Makoto Kinoshita, and Shinichi Iwasaki, and Chisato Fujimoto, and Aki Inoue, and Naoya Egami, and Yasuhiro Chihara, and Munetaka Ushio, and Tatsuya Yamasoba
July 2009, Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
Makoto Kinoshita, and Shinichi Iwasaki, and Chisato Fujimoto, and Aki Inoue, and Naoya Egami, and Yasuhiro Chihara, and Munetaka Ushio, and Tatsuya Yamasoba
April 2016, Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
Makoto Kinoshita, and Shinichi Iwasaki, and Chisato Fujimoto, and Aki Inoue, and Naoya Egami, and Yasuhiro Chihara, and Munetaka Ushio, and Tatsuya Yamasoba
January 2012, Ear and hearing,
Copied contents to your clipboard!