Anterior and pan-endophthalmitis caused by Candida albicans and Aspergillus fumigatus: report of two cases. 2013

Anan Wang, and Jianxiong Cao, and Shufang Hu, and Zhenquan Zhao, and Mingling Wang, and Tianlin Xiao
Eye Hospital of Wenzhou Medical College, Wenzhou, Zhejiang, China.

We report two posttraumatic fungal endophthalmitis cases with anterior and entire segment involvement caused, respectively, by Candida albicans and Aspergillus fumigatus. The anterior endophthalmitis induced by C. albicans presented multifocal lesions with hyphael structures in anterior chamber, but without involvement of posterior vitreous. The pan-endophthalmitis caused by A. fumigatus displayed significant hypopyon and vitritis. Treatment strategies are anterior chamber cleaning for anterior endophthalmitis and vitrectomy for pan-endophthalmitis, excepting systemic and topical antifungal drug applications including intravitreal injection for both types of endophthalmitis. There is a much better outcome in the case with anterior segment involvement than that with entire segment involvement. This case report provides evidence that the different types of posttraumatic fungal endophthalmitis related to different fungal infections indeed existed and should be managed with different strategies.

UI MeSH Term Description Entries
D009877 Endophthalmitis Suppurative inflammation of the tissues of the internal structures of the eye frequently associated with an infection. Ophthalmia,Infectious Endophthalmitis,Endophthalmitides,Endophthalmitides, Infectious,Endophthalmitis, Infectious,Infectious Endophthalmitides,Ophthalmias
D002176 Candida albicans A unicellular budding fungus which is the principal pathogenic species causing CANDIDIASIS (moniliasis). Candida albicans var. stellatoidea,Candida stellatoidea,Dematium albicans,Monilia albicans,Myceloblastanon albicans,Mycotorula albicans,Parasaccharomyces albicans,Procandida albicans,Procandida stellatoidea,Saccharomyces albicans,Syringospora albicans
D002177 Candidiasis Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed) Candida Infection,Moniliasis,Candida Infections,Candidiases,Infection, Candida,Moniliases
D003646 Debridement The removal of foreign material and devitalized or contaminated tissue from or adjacent to a traumatic or infected lesion until surrounding healthy tissue is exposed. (Dorland, 27th ed) Debridements
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000935 Antifungal Agents Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. Anti-Fungal Agents,Antifungal Agent,Fungicides, Therapeutic,Antibiotics, Antifungal,Therapeutic Fungicides,Agent, Antifungal,Anti Fungal Agents,Antifungal Antibiotics
D001228 Aspergillosis Infections with fungi of the genus ASPERGILLUS. Aspergillus Infection,Aspergilloses,Aspergillus Infections,Infection, Aspergillus,Infections, Aspergillus
D001232 Aspergillus fumigatus A species of imperfect fungi from which the antibiotic fumigatin is obtained. Its spores may cause respiratory infection in birds and mammals. Aspergillus fumigates,Neosartorya fumigata,Sartorya fumigata

Related Publications

Anan Wang, and Jianxiong Cao, and Shufang Hu, and Zhenquan Zhao, and Mingling Wang, and Tianlin Xiao
February 2005, Anales de medicina interna (Madrid, Spain : 1984),
Anan Wang, and Jianxiong Cao, and Shufang Hu, and Zhenquan Zhao, and Mingling Wang, and Tianlin Xiao
October 2012, Acta medica Indonesiana,
Anan Wang, and Jianxiong Cao, and Shufang Hu, and Zhenquan Zhao, and Mingling Wang, and Tianlin Xiao
September 1981, ZWR,
Anan Wang, and Jianxiong Cao, and Shufang Hu, and Zhenquan Zhao, and Mingling Wang, and Tianlin Xiao
September 1962, Archives of ophthalmology (Chicago, Ill. : 1960),
Anan Wang, and Jianxiong Cao, and Shufang Hu, and Zhenquan Zhao, and Mingling Wang, and Tianlin Xiao
June 1975, The Journal of infectious diseases,
Anan Wang, and Jianxiong Cao, and Shufang Hu, and Zhenquan Zhao, and Mingling Wang, and Tianlin Xiao
January 1991, Reviews of infectious diseases,
Anan Wang, and Jianxiong Cao, and Shufang Hu, and Zhenquan Zhao, and Mingling Wang, and Tianlin Xiao
February 1983, Nederlands tijdschrift voor geneeskunde,
Anan Wang, and Jianxiong Cao, and Shufang Hu, and Zhenquan Zhao, and Mingling Wang, and Tianlin Xiao
January 1982, Mykosen,
Anan Wang, and Jianxiong Cao, and Shufang Hu, and Zhenquan Zhao, and Mingling Wang, and Tianlin Xiao
February 2006, Pathology,
Anan Wang, and Jianxiong Cao, and Shufang Hu, and Zhenquan Zhao, and Mingling Wang, and Tianlin Xiao
December 1987, Acta ophthalmologica,
Copied contents to your clipboard!