Classification of sleep apnea using wavelet-based spectral analysis of heart rate variability. 2013

A Hossen, and D Jaju, and B Al-Ghunaimi, and B Al-Faqeer, and T Al-Yahyai, and M O Hassan, and M Al-Abri
Department of Electrical and Computer Engineering, College of Engineering, Sultan Qaboos University, Muscat, Oman. abhossen@squ.edu.om

BACKGROUND Obstructive Sleep Apnea (OSA) is the cessation of breathing during sleep due to the collapse of upper airway. Polysomnographic recording is a conventional method for detection of OSA. Although it provides reliable results, it is expensive and cumbersome. Thus, an advanced non-invasive signal processing based technique is needed. OBJECTIVE The main purpose of this work is to predict the severity of sleep apnea using an efficient wavelet-based spectral analysis method of the heart rate variability (HRV) to classify sleep apnea into three different levels (mild, moderate, and severe) according to its severity and to distinguish them from normal subjects. METHODS The standard FFT spectrum analysis method and the soft-decision wavelet-based technique are to be used in this work in order to rank patients to full polysomnography. Data of 20 normal subjects and 20 patients with mild apnea and 20 patients with moderate apnea and 20 patients of severe apnea are used in this study. The data is obtained from the sleep laboratory of Sultan Qaboos University hospital in Oman. Four different classification versions have been used in this work. RESULTS Accuracy result of 90% was obtained between severe and normal subjects and 85% between mild and normal and 75% between severe and moderate and 83.75% between normal and patients. CONCLUSIONS The VLF/LF power spectral ratio of the wavelet-based soft-decision analysis of the RRI data after a high-pass filter resulted in the best accuracy of classification in all versions.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D005260 Female Females
D005583 Fourier Analysis Analysis based on the mathematical function first formulated by Jean-Baptiste-Joseph Fourier in 1807. The function, known as the Fourier transform, describes the sinusoidal pattern of any fluctuating pattern in the physical world in terms of its amplitude and its phase. It has broad applications in biomedicine, e.g., analysis of the x-ray crystallography data pivotal in identifying the double helical nature of DNA and in analysis of other molecules, including viruses, and the modified back-projection algorithm universally used in computerized tomography imaging, etc. (From Segen, The Dictionary of Modern Medicine, 1992) Fourier Series,Fourier Transform,Analysis, Cyclic,Analysis, Fourier,Cyclic Analysis,Analyses, Cyclic,Cyclic Analyses,Series, Fourier,Transform, Fourier
D006333 Heart Failure A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. Cardiac Failure,Heart Decompensation,Congestive Heart Failure,Heart Failure, Congestive,Heart Failure, Left-Sided,Heart Failure, Right-Sided,Left-Sided Heart Failure,Myocardial Failure,Right-Sided Heart Failure,Decompensation, Heart,Heart Failure, Left Sided,Heart Failure, Right Sided,Left Sided Heart Failure,Right Sided Heart Failure
D006339 Heart Rate The number of times the HEART VENTRICLES contract per unit of time, usually per minute. Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

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