Biomaterial Database

Myocardial oxygen consumption at rest and during submaximal exercise: effects of increased adiposity. 2013

R Rajalakshmi, and Vijaya Y Vageesh, and S M Nataraj

Department of Physiology, JSS Medical College, Constituent College of JSS University, Mysore 570015, India. rajashk_7@yahoo.co.in

Overweight and obesity are major risk factors for cardiovascular diseases. The objective of this study was to determine the effect of increased adiposity on myocardial oxygen consumption at rest and during submaximal exercise in young adults. The study consisted of 85 young adults (18-22 years) grouped into 3 based on their body mass index as normal (NW, n=30), overweight (OW, n=25) and obese (OB, n=30). Steady dynamic exercise test equivalent to Grade 2 Bruce protocol was carried out on treadmill for 5min. Blood pressure and heart rate were recorded before, during 3rd min of exercise, immediately after cessation of exercise and during 5th min of recovery. MVO2 was measured by the Rate Pressure Product (RPP) calculated as product of heart rate and systolic blood pressure. Statistical analysis was done using ANOVA and regression analysis. The mean resting RPP was significantly higher in overweight and obese groups when compared with the normal weight group (p<0.05). There was significant increase in RPP changes to exercise [mean difference in NW-8270.93 bpm.mmHg (99.61%), OW-10593.12 bpm.mmHg (118.39%) and OB-10897.33 bpm.mmHg (118.10%), p< 0.05] and the value did not return to baseline after 5 mins of recovery in study groups (p< 0.05). BMI and Waist stature ratio were the most important independent parameters in prediction of RPP. The study shows that overweight and obese young adults have elevated resting RPP and much higher RPP response to exercise indicating increased (MVO2) at rest and during exercise suggesting higher hemodynamic stress to the heart.

UI	MeSH Term	Description	Entries
D010101	Oxygen Consumption	The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)	Consumption, Oxygen,Consumptions, Oxygen,Oxygen Consumptions
D001794	Blood Pressure	PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.	Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D005080	Exercise Test	Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.	Arm Ergometry Test,Bicycle Ergometry Test,Cardiopulmonary Exercise Testing,Exercise Testing,Step Test,Stress Test,Treadmill Test,Cardiopulmonary Exercise Test,EuroFit Tests,Eurofit Test Battery,European Fitness Testing Battery,Fitness Testing,Physical Fitness Testing,Arm Ergometry Tests,Bicycle Ergometry Tests,Cardiopulmonary Exercise Tests,Ergometry Test, Arm,Ergometry Test, Bicycle,Ergometry Tests, Arm,Ergometry Tests, Bicycle,EuroFit Test,Eurofit Test Batteries,Exercise Test, Cardiopulmonary,Exercise Testing, Cardiopulmonary,Exercise Tests,Exercise Tests, Cardiopulmonary,Fitness Testing, Physical,Fitness Testings,Step Tests,Stress Tests,Test Battery, Eurofit,Test, Arm Ergometry,Test, Bicycle Ergometry,Test, Cardiopulmonary Exercise,Test, EuroFit,Test, Exercise,Test, Step,Test, Stress,Test, Treadmill,Testing, Cardiopulmonary Exercise,Testing, Exercise,Testing, Fitness,Testing, Physical Fitness,Tests, Arm Ergometry,Tests, Bicycle Ergometry,Tests, Cardiopulmonary Exercise,Tests, EuroFit,Tests, Exercise,Tests, Step,Tests, Stress,Tests, Treadmill,Treadmill Tests
D006339	Heart Rate	The number of times the HEART VENTRICLES contract per unit of time, usually per minute.	Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D015444	Exercise	Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.	Aerobic Exercise,Exercise, Aerobic,Exercise, Isometric,Exercise, Physical,Isometric Exercise,Physical Activity,Acute Exercise,Exercise Training,Activities, Physical,Activity, Physical,Acute Exercises,Aerobic Exercises,Exercise Trainings,Exercise, Acute,Exercises,Exercises, Acute,Exercises, Aerobic,Exercises, Isometric,Exercises, Physical,Isometric Exercises,Physical Activities,Physical Exercise,Physical Exercises,Training, Exercise,Trainings, Exercise
D050154	Adiposity	The amount of fat or lipid deposit at a site or an organ in the body, an indicator of body fat status.