BIOMAT Database Logo BIOMAT Database Logo

Copper-catalyzed free-radical C-H arylation of pyrroles. 2014

Aurélien Honraedt, and Marie-Audrey Raux, and Erwan Le Grognec, and Denis Jacquemin, and François-Xavier Felpin
Université de Nantes, UFR Sciences et Techniques, UMR CNRS 6230, CEISAM, 2 rue de la Houssinière, BP 92208, 44322 Nantes Cedex 3, France. fx.felpin@univ-nantes.fr.

A room temperature copper-catalyzed radical arylation of pyrroles with anilines, through in situ generated aryl diazonium salts, has been developed under neutral conditions. Experimental and theoretical studies explain the crucial role of CaCO3 and the high regioselectivity observed.

UI MeSH Term Description Entries

Related Publications

Aurélien Honraedt, and Marie-Audrey Raux, and Erwan Le Grognec, and Denis Jacquemin, and François-Xavier Felpin
Phosphine-free palladium-catalyzed C-H bond arylation of free (N-H)-indoles and pyrroles.
February 2007, The Journal of organic chemistry,
Aurélien Honraedt, and Marie-Audrey Raux, and Erwan Le Grognec, and Denis Jacquemin, and François-Xavier Felpin
Palladium-catalyzed C-H arylation of 2,5-substituted pyrroles.
January 2011, Organic letters,
Aurélien Honraedt, and Marie-Audrey Raux, and Erwan Le Grognec, and Denis Jacquemin, and François-Xavier Felpin
Enantioselective Arylation of Benzylic C-H Bonds by Copper-Catalyzed Radical Relay.
May 2019, Angewandte Chemie (International ed. in English),
Aurélien Honraedt, and Marie-Audrey Raux, and Erwan Le Grognec, and Denis Jacquemin, and François-Xavier Felpin
Copper-catalyzed arylation of heterocycle C-H bonds.
October 2007, Journal of the American Chemical Society,
Aurélien Honraedt, and Marie-Audrey Raux, and Erwan Le Grognec, and Denis Jacquemin, and François-Xavier Felpin
Photoinduced Copper-Catalyzed C-H Arylation at Room Temperature.
April 2016, Angewandte Chemie (International ed. in English),
Aurélien Honraedt, and Marie-Audrey Raux, and Erwan Le Grognec, and Denis Jacquemin, and François-Xavier Felpin
A meta-selective copper-catalyzed C-H bond arylation.
March 2009, Science (New York, N.Y.),
Aurélien Honraedt, and Marie-Audrey Raux, and Erwan Le Grognec, and Denis Jacquemin, and François-Xavier Felpin
Copper-catalyzed arylation and alkenylation of polyfluoroarene C-H bonds.
January 2008, Journal of the American Chemical Society,
Aurélien Honraedt, and Marie-Audrey Raux, and Erwan Le Grognec, and Denis Jacquemin, and François-Xavier Felpin
Cobalt-Mediated Photochemical C-H Arylation of Pyrroles.
May 2024, Angewandte Chemie (International ed. in English),
Aurélien Honraedt, and Marie-Audrey Raux, and Erwan Le Grognec, and Denis Jacquemin, and François-Xavier Felpin
Triethanolamine-mediated palladium-catalyzed regioselective C-2 direct arylation of free NH-pyrroles.
May 2010, The Journal of organic chemistry,
Aurélien Honraedt, and Marie-Audrey Raux, and Erwan Le Grognec, and Denis Jacquemin, and François-Xavier Felpin
δ C-H (hetero)arylation via Cu-catalyzed radical relay.
January 2019, Chemical science,
Copied contents to your clipboard!