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Once-daily naftifine cream 1% in the treatment of tinea cruris and tinea corporis. 1990
R E Jordon, and
R P Rapini, and
I H Rex, and
H I Katz, and
J G Hickman, and
J W Bard, and
R S Medansky, and
D A Lew-Kaya, and
J Sefton, and
R E DeGryse
Department of Medicine, University of Texas Health Science Center, Houston.
Seventy patients with tinea cruris or tinea corporis were treated with naftifine cream 1% or vehicle once daily for 4 weeks in this double-blind, randomized study. After two weeks, the patients using naftifine had a significantly higher mycologic cure rate than the vehicle-treated patients (79% vs. 31%, p less than 0.001), and they showed significantly better resolution of signs and symptoms. Statistically significantly differences favoring naftifine over its vehicle were found throughout the treatment period and 2 weeks posttreatment.
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