-transparent.png){kind=logo}
Localization of lysozyme mRNA in the labial salivary glands by in situ hybridization in Sjögren's syndrome. 1990
Y T Konttinen, and
M Kulomaa, and
M Segerberg-Konttinen, and
D Nordström, and
R Keinänen, and
M Grönblad, and
M Malmström
Fourth Department of Medicine, Helsinki University Central Hospital, Finland.
In this study, lysozyme mRNA in labial salivary glands has been localized with in situ hybridization technique using 35S-labeled hen lysozyme cDNA (cDNALZM) as a hybridization probe in normals and in patients with Sjögren's syndrome, 35S-DNALZM:mRNA hybrids were detected only in acinar serous cells, although lysozyme was identified in ductal cells using immunohistochemical techniques. Our results suggest that the serous acinar cells are the only site of lysozyme synthesis in small salivary glands. The presence of lysozyme in ductal cells may be a result of reabsorption from the saliva or concentration from the blood or surrounding tissues.
Related Publications
Y T Konttinen, and
M Kulomaa, and
M Segerberg-Konttinen, and
D Nordström, and
R Keinänen, and
M Grönblad, and
M Malmström
March 1974,
The Bulletin of Tokyo Medical and Dental University,
Y T Konttinen, and
M Kulomaa, and
M Segerberg-Konttinen, and
D Nordström, and
R Keinänen, and
M Grönblad, and
M Malmström
June 1978,
Journal of oral pathology,
Y T Konttinen, and
M Kulomaa, and
M Segerberg-Konttinen, and
D Nordström, and
R Keinänen, and
M Grönblad, and
M Malmström
March 1981,
Ceskoslovenska stomatologie,
Y T Konttinen, and
M Kulomaa, and
M Segerberg-Konttinen, and
D Nordström, and
R Keinänen, and
M Grönblad, and
M Malmström
January 1974,
Arthritis and rheumatism,
Y T Konttinen, and
M Kulomaa, and
M Segerberg-Konttinen, and
D Nordström, and
R Keinänen, and
M Grönblad, and
M Malmström
January 1998,
Autoimmunity,
Y T Konttinen, and
M Kulomaa, and
M Segerberg-Konttinen, and
D Nordström, and
R Keinänen, and
M Grönblad, and
M Malmström
July 1994,
European journal of cancer. Part B, Oral oncology,
Y T Konttinen, and
M Kulomaa, and
M Segerberg-Konttinen, and
D Nordström, and
R Keinänen, and
M Grönblad, and
M Malmström
July 1992,
Arthritis and rheumatism,
Y T Konttinen, and
M Kulomaa, and
M Segerberg-Konttinen, and
D Nordström, and
R Keinänen, and
M Grönblad, and
M Malmström
August 2012,
Clinical and experimental immunology,
Y T Konttinen, and
M Kulomaa, and
M Segerberg-Konttinen, and
D Nordström, and
R Keinänen, and
M Grönblad, and
M Malmström
May 1997,
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology,
Y T Konttinen, and
M Kulomaa, and
M Segerberg-Konttinen, and
D Nordström, and
R Keinänen, and
M Grönblad, and
M Malmström
January 1996,
The Journal of rheumatology,
