Effect of diurnal variation on debrisoquine metabolic phenotyping. 1990

G L Shaw, and R T Falk, and N E Caporaso, and H J Issaq, and R G Kase, and S D Fox, and M A Tucker
Environmental Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

UI MeSH Term Description Entries
D007546 Isoquinolines A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
D008297 Male Males
D010641 Phenotype The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment. Phenotypes
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D002940 Circadian Rhythm The regular recurrence, in cycles of about 24 hours, of biological processes or activities, such as sensitivity to drugs or environmental and physiological stimuli. Diurnal Rhythm,Nyctohemeral Rhythm,Twenty-Four Hour Rhythm,Nycthemeral Rhythm,Circadian Rhythms,Diurnal Rhythms,Nycthemeral Rhythms,Nyctohemeral Rhythms,Rhythm, Circadian,Rhythm, Diurnal,Rhythm, Nycthemeral,Rhythm, Nyctohemeral,Rhythm, Twenty-Four Hour,Rhythms, Circadian,Rhythms, Diurnal,Rhythms, Nycthemeral,Rhythms, Nyctohemeral,Rhythms, Twenty-Four Hour,Twenty Four Hour Rhythm,Twenty-Four Hour Rhythms
D003647 Debrisoquin An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism. Debrisoquine,Tendor
D004435 Eating The consumption of edible substances. Dietary Intake,Feed Intake,Food Intake,Macronutrient Intake,Micronutrient Intake,Nutrient Intake,Nutritional Intake,Ingestion,Dietary Intakes,Feed Intakes,Intake, Dietary,Intake, Feed,Intake, Food,Intake, Macronutrient,Intake, Micronutrient,Intake, Nutrient,Intake, Nutritional,Macronutrient Intakes,Micronutrient Intakes,Nutrient Intakes,Nutritional Intakes
D005215 Fasting Abstaining from FOOD. Hunger Strike,Hunger Strikes,Strike, Hunger,Strikes, Hunger
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

G L Shaw, and R T Falk, and N E Caporaso, and H J Issaq, and R G Kase, and S D Fox, and M A Tucker
January 1988, European journal of clinical pharmacology,
G L Shaw, and R T Falk, and N E Caporaso, and H J Issaq, and R G Kase, and S D Fox, and M A Tucker
May 1990, International journal of clinical pharmacology, therapy, and toxicology,
G L Shaw, and R T Falk, and N E Caporaso, and H J Issaq, and R G Kase, and S D Fox, and M A Tucker
January 1992, Drug metabolism and drug interactions,
G L Shaw, and R T Falk, and N E Caporaso, and H J Issaq, and R G Kase, and S D Fox, and M A Tucker
January 1992, Psychopharmacology bulletin,
G L Shaw, and R T Falk, and N E Caporaso, and H J Issaq, and R G Kase, and S D Fox, and M A Tucker
January 1989, European journal of clinical pharmacology,
G L Shaw, and R T Falk, and N E Caporaso, and H J Issaq, and R G Kase, and S D Fox, and M A Tucker
December 1990, Die Pharmazie,
G L Shaw, and R T Falk, and N E Caporaso, and H J Issaq, and R G Kase, and S D Fox, and M A Tucker
January 1991, Therapie,
G L Shaw, and R T Falk, and N E Caporaso, and H J Issaq, and R G Kase, and S D Fox, and M A Tucker
June 1973, The Journal of clinical endocrinology and metabolism,
G L Shaw, and R T Falk, and N E Caporaso, and H J Issaq, and R G Kase, and S D Fox, and M A Tucker
April 2007, The Chinese journal of physiology,
G L Shaw, and R T Falk, and N E Caporaso, and H J Issaq, and R G Kase, and S D Fox, and M A Tucker
September 1990, Lancet (London, England),
Copied contents to your clipboard!