BIOMAT Database Logo BIOMAT Database Logo

Epiretinal macular edema associated with thick epiretinal membranes. 2013

Rishi R Doshi, and Matthew D Lowrance, and Brian T Kim, and Janet L Davis, and Philip J Rosenfeld

High-resolution imaging with spectral-domain optical coherence tomography has identified an unusual group of epiretinal membranes (ERMs) in the presence of lamellar macular holes. These ERMs are unusually thick. The authors present the case of a patient with age-related macular degeneration who developed edema within a thickened ERM in both eyes after cataract surgery. The edema resolved with anti-vascular endothelial growth factor (VEGF) therapy. The authors propose that the VEGF-responsive fluid within these thick ERMs arose from fibrovascular tissue derived from the retina. Further studies with histopathology will be required to determine whether neovascular tissue is present in all cases of thickened ERMs with epiretinal edema.

UI MeSH Term Description Entries
D008268 Macular Degeneration Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms. Maculopathy,Maculopathy, Age-Related,Age-Related Macular Degeneration,Age-Related Maculopathies,Age-Related Maculopathy,Macular Degeneration, Age-Related,Macular Dystrophy,Maculopathies, Age-Related,Age Related Macular Degeneration,Age Related Maculopathies,Age Related Maculopathy,Age-Related Macular Degenerations,Degeneration, Macular,Dystrophy, Macular,Macular Degeneration, Age Related,Macular Degenerations,Macular Dystrophies,Maculopathies,Maculopathy, Age Related
D008269 Macular Edema Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90) Central Retinal Edema, Cystoid,Cystoid Macular Edema,Macular Edema, Cystoid,Cystoid Macular Dystrophy,Cystoid Macular Edema, Postoperative,Irvine-Gass Syndrome,Macular Dystrophy, Dominant Cystoid,Edema, Cystoid Macular,Edema, Macular,Irvine Gass Syndrome,Syndrome, Irvine-Gass
D008297 Male Males
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old
D019773 Epiretinal Membrane A membrane on the vitreal surface of the retina resulting from the proliferation of one or more of three retinal elements: (1) fibrous astrocytes; (2) fibrocytes; and (3) RETINAL PIGMENT EPITHELIUM. Localized epiretinal membranes may occur at the posterior pole of the eye without clinical signs or may cause marked loss of vision as a result of covering, distorting, or detaching the FOVEA CENTRALIS. Epiretinal membranes may cause vascular leakage and secondary retinal edema. In younger individuals some membranes appear to be developmental in origin and occur in otherwise normal eyes. The majority occur in association with RETINAL HOLES, ocular concussions, retinal inflammation, or after ocular surgery. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p291) Cellophane Maculopathy,Epimacular Membrane,Macular Puckers,Premacular Fibrosis,Preretinal Macular Fibrosis,Preretinal Membrane,Surface-Wrinkling Retinopathy,Cellophane Maculopathies,Epimacular Membranes,Epiretinal Membranes,Fibrosis, Premacular,Fibrosis, Preretinal Macular,Macular Fibrosis, Preretinal,Macular Pucker,Maculopathy, Cellophane,Membrane, Epimacular,Membrane, Epiretinal,Membrane, Preretinal,Premacular Fibroses,Preretinal Macular Fibroses,Preretinal Membranes,Pucker, Macular,Retinopathy, Surface-Wrinkling,Surface Wrinkling Retinopathy,Surface-Wrinkling Retinopathies
D041623 Tomography, Optical Coherence An imaging method using LASERS that is used for mapping subsurface structure. When a reflective site in the sample is at the same optical path length (coherence) as the reference mirror, the detector observes interference fringes. OCT Tomography,Optical Coherence Tomography,Coherence Tomography, Optical,Tomography, OCT

Related Publications

Rishi R Doshi, and Matthew D Lowrance, and Brian T Kim, and Janet L Davis, and Philip J Rosenfeld
Thick Epiretinal Membranes Associated with Lamellar Macular Holes.
January 2017, Ophthalmology. Retina,
Rishi R Doshi, and Matthew D Lowrance, and Brian T Kim, and Janet L Davis, and Philip J Rosenfeld
[Association of epiretinal membranes with macular edema in pars planitis].
January 2014, Archivos de la Sociedad Espanola de Oftalmologia,
Rishi R Doshi, and Matthew D Lowrance, and Brian T Kim, and Janet L Davis, and Philip J Rosenfeld
Pseudophakic macular edema involving epiretinal proliferation associated with macular hole.
November 2020, Indian journal of ophthalmology,
Rishi R Doshi, and Matthew D Lowrance, and Brian T Kim, and Janet L Davis, and Philip J Rosenfeld
Ultrastructure of epiretinal membranes associated with macular holes.
April 1998, Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,
Rishi R Doshi, and Matthew D Lowrance, and Brian T Kim, and Janet L Davis, and Philip J Rosenfeld
[Epiretinal macular membranes].
January 2005, Oftalmologia (Bucharest, Romania : 1990),
Rishi R Doshi, and Matthew D Lowrance, and Brian T Kim, and Janet L Davis, and Philip J Rosenfeld
Macular epiretinal membranes.
June 2000, Seminars in ophthalmology,
Rishi R Doshi, and Matthew D Lowrance, and Brian T Kim, and Janet L Davis, and Philip J Rosenfeld
Preexisting epiretinal membrane is associated with pseudophakic cystoid macular edema.
May 2018, Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,
Rishi R Doshi, and Matthew D Lowrance, and Brian T Kim, and Janet L Davis, and Philip J Rosenfeld
Epiretinal pathology of diffuse diabetic macular edema associated with vitreomacular traction.
April 2005, American journal of ophthalmology,
Rishi R Doshi, and Matthew D Lowrance, and Brian T Kim, and Janet L Davis, and Philip J Rosenfeld
Increased risk of postsurgical macular edema in high stage idiopathic epiretinal membranes.
August 2021, Eye and vision (London, England),
Rishi R Doshi, and Matthew D Lowrance, and Brian T Kim, and Janet L Davis, and Philip J Rosenfeld
Lack of Evidence for Vasoactive and Inflammatory Mediators in the Promotion of Macular Edema Associated with Epiretinal Membranes.
September 2017, Scientific reports,
Copied contents to your clipboard!