Biomaterial Database

Mycoplasma in relation to gingivitis and periodontitis. 1990

H S Kwek, and M Wilson, and H N Newman

Institute of Dental Surgery, Eastman Dental Hospital, London, UK.

In this study, mycoplasma were enumerated in the gingival crevicular fluid (GCF) of gingivitis and periodontitis patients. GCF samples were obtained from the mesial (approximal) gingival crevice or periodontal pocket of the maxillary right first permanent molar. Samples were cultured anaerobically on a medium selective for mycoplasmas as well as on a non-selective medium to obtain a total anaerobic count. Mycoplasmas were present in the GCF of both gingivitis and periodontitis patients, but a greater % was obtained from the GCF of patients with periodontitis. The proportions of mycoplasma appeared to be independent of the disease activity as expressed by bleeding on probing (PBI), but to be related to probable pocket depth, as shown by the higher %s in periodontitis than gingivitis for a given PBI. On the basis of an increased proportion in relation to disease severity, mycoplasmas would therefore appear to be amongst those micro-organisms associated with CIPD.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009174	Mycoplasma	A genus of gram-negative, mostly facultatively anaerobic bacteria in the family MYCOPLASMATACEAE. The cells are bounded by a PLASMA MEMBRANE and lack a true CELL WALL. Its organisms are pathogens found on the MUCOUS MEMBRANES of humans, ANIMALS, and BIRDS.	Eperythrozoon,Haemobartonella,Mycoplasma putrefaciens,PPLO,Pleuropneumonia-Like Organisms,Pleuropneumonia Like Organisms
D010514	Periodontal Pocket	An abnormal extension of a gingival sulcus accompanied by the apical migration of the epithelial attachment and bone resorption.	Pocket, Periodontal,Periodontal Pockets,Pockets, Periodontal
D010518	Periodontitis	Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)	Pericementitis,Pericementitides,Periodontitides
D002908	Chronic Disease	Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).	Chronic Condition,Chronic Illness,Chronically Ill,Chronic Conditions,Chronic Diseases,Chronic Illnesses,Condition, Chronic,Disease, Chronic,Illness, Chronic
D005260	Female		Females
D005883	Gingival Crevicular Fluid	A fluid occurring in minute amounts in the gingival crevice, believed by some authorities to be an inflammatory exudate and by others to cleanse material from the crevice, containing sticky plasma proteins which improve adhesions of the epithelial attachment, have antimicrobial properties, and exert antibody activity. (From Jablonski, Illustrated Dictionary of Dentistry, 1982)	Gingival Exudate,Crevicular Fluid, Gingival,Crevicular Fluids, Gingival,Exudate, Gingival,Exudates, Gingival,Fluid, Gingival Crevicular,Fluids, Gingival Crevicular,Gingival Crevicular Fluids,Gingival Exudates
D005891	Gingivitis	Inflammation of gum tissue (GINGIVA) without loss of connective tissue.	Gingivitides
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man