-transparent.png){kind=logo}
Knowledge of the antigens recognized during allograft rejection is still incomplete. Cloned cytotoxic T lymphocytes were used to study the distribution of target determinants in the dog. CTL clones were obtained with a limiting dilution technique from effector cells generated in mixed lymphocyte culture. The clones have been tested for cell-mediated cytotoxicity against PHA-stimulated lymphoblasts, monocytes, and arterial and venous endothelial cells. A limited number of patterns of lysis of one, or more than one, of the four different target cells was observed. The nature of the possible target determinants recognized by these CTL-clones is discussed.
Related Publications
G Groenewegen, and
W A Buurman, and
C J van der Linden, and
G M Jeunhomme, and
G Kootstra
October 1987,
The Journal of experimental medicine,
G Groenewegen, and
W A Buurman, and
C J van der Linden, and
G M Jeunhomme, and
G Kootstra
December 1988,
Immunobiology,
G Groenewegen, and
W A Buurman, and
C J van der Linden, and
G M Jeunhomme, and
G Kootstra
July 1981,
Tissue antigens,
G Groenewegen, and
W A Buurman, and
C J van der Linden, and
G M Jeunhomme, and
G Kootstra
October 1984,
Journal of immunology (Baltimore, Md. : 1950),
G Groenewegen, and
W A Buurman, and
C J van der Linden, and
G M Jeunhomme, and
G Kootstra
November 1974,
Nature,
G Groenewegen, and
W A Buurman, and
C J van der Linden, and
G M Jeunhomme, and
G Kootstra
October 1977,
American journal of veterinary research,
G Groenewegen, and
W A Buurman, and
C J van der Linden, and
G M Jeunhomme, and
G Kootstra
August 1985,
Experimental hematology,
G Groenewegen, and
W A Buurman, and
C J van der Linden, and
G M Jeunhomme, and
G Kootstra
January 1980,
Infection and immunity,
G Groenewegen, and
W A Buurman, and
C J van der Linden, and
G M Jeunhomme, and
G Kootstra
January 1982,
Immunogenetics,
G Groenewegen, and
W A Buurman, and
C J van der Linden, and
G M Jeunhomme, and
G Kootstra
January 1981,
Immunogenetics,
