Biomaterial Database

Staining procedure to aid in assessment of bucrylate histotoxicity in tissue sections. 1985

M J Lundie, and D Ellyatt, and J C Kaufmann, and H V Vinters

Isobutyl-2-cyanoacrylate (bucrylate) is commonly used as a material for therapeutic embolization. Histologic sections of embolized tissue routinely stained with hematoxylin-eosin show the bucrylate as a translucent material. We outline a staining procedure that demonstrates bucrylate in tissue sections. It is useful in routinely prepared paraffin-embedded tissue, and it is also effective after embolized tissues have been processed with petroleum ether rather than xylene. This stain may be effectively utilized to assess harmful tissue reactions to bucrylate.

UI	MeSH Term	Description	Entries
D002015	Bucrylate	Cyanoacrylate tissue adhesive also used to occlude blood vessels supplying neoplastic or other diseased tissue.	Isobutylcyanoacrylate,Bucrilate,Isobutyl Cyanoacrylate,Isobutyl alpha-Cyanoacrylate,Isobutyl-2-cyanoacrylate,Cyanoacrylate, Isobutyl,Isobutyl 2 cyanoacrylate,Isobutyl alpha Cyanoacrylate,alpha-Cyanoacrylate, Isobutyl
D003487	Cyanoacrylates	A group of compounds having the general formula CH2	Cyanoacrylate
D004621	Embolization, Therapeutic	A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.	Embolotherapy,Therapeutic Embolization,Embolizations, Therapeutic,Embolotherapies,Therapeutic Embolizations
D006652	Histological Techniques	Methods of preparing tissue for examination and study of the origin, structure, function, or pathology.	Histologic Technic,Histologic Technics,Histologic Technique,Histologic Techniques,Histological Technics,Technic, Histologic,Technics, Histologic,Technique, Histologic,Techniques, Histologic,Histological Technic,Histological Technique,Technic, Histological,Technics, Histological,Technique, Histological,Techniques, Histological
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001165	Arteriovenous Malformations	Abnormal formation of blood vessels that shunt arterial blood directly into veins without passing through the CAPILLARIES. They usually are crooked, dilated, and with thick vessel walls. A common type is the congenital arteriovenous fistula. The lack of blood flow and oxygen in the capillaries can lead to tissue damage in the affected areas.	Arteriovenous Malformation,Malformation, Arteriovenous,Malformations, Arteriovenous
D013194	Staining and Labeling	The marking of biological material with a dye or other reagent for the purpose of identifying and quantitating components of tissues, cells or their extracts.	Histological Labeling,Staining,Histological Labelings,Labeling and Staining,Labeling, Histological,Labelings, Histological,Stainings