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Treatment of non-small cell lung cancer (NSCLC). 2013
Konstantinos Zarogoulidis, and
Paul Zarogoulidis, and
Kaid Darwiche, and
Efimia Boutsikou, and
Nikolaos Machairiotis, and
Kosmas Tsakiridis, and
Nikolaos Katsikogiannis, and
Ioanna Kougioumtzi, and
Ilias Karapantzos, and
Haidong Huang, and
Dionysios Spyratos
Pulmonary Department-Oncology Unit, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece;
Radical surgery is the standard of care for fit stage I non-small cell lung cancer (NSCLC) patients. Adjuvant treatment should be offered only as part of an investigation trial. Stage II and IIIA adjuvant cisplatin-based chemotherapy remains the gold standard for completely resected NSCLC tumors. Additionally radiotherapy should be offered in patients with N2 lymph nodes. In advanced stage IIIB/IV or inoperable NSCLC pts, a multidisciplinary treatment should be offered consisted of 4 cycles of cisplatin-based chemotherapy plus a 3(rd) generation cytotoxic agent or a cytostatic (anti-EGFR, anti-VEGFR) drug.
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