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An average of 20 X 10(6) nucleated cells were obtained from 1 g tissue of human benign prostatic hyperplasia by mechanical separation technique. Of these cells, 96.2% showed acid phosphatase activity and this was 10 times higher than the remaining stromal fraction on a protein base. The total activity of 5 alpha-reductase was 81 times higher in stroma than epithelium and the total activity of 3(beta)-oxidoreductase was 29 times higher in stroma. Androgen receptor amount measured in total tissue, epithelium and stroma were 100, 29 and 62 fmol R1881/mg DNA, respectively. These results suggest that androgen metabolism takes place mainly in the stroma of human BPH tissue, and that BPH is probably the disease of prostatic stroma.
K Oishi, and
K Okada, and
O Yoshida, and
J C Romijn, and
J Bolt de Vries, and
F H Schröder
November 1994,
Steroids,
K Oishi, and
K Okada, and
O Yoshida, and
J C Romijn, and
J Bolt de Vries, and
F H Schröder
August 1982,
Acta endocrinologica,
K Oishi, and
K Okada, and
O Yoshida, and
J C Romijn, and
J Bolt de Vries, and
F H Schröder
January 1997,
Khirurgiia,
K Oishi, and
K Okada, and
O Yoshida, and
J C Romijn, and
J Bolt de Vries, and
F H Schröder
June 1980,
Acta endocrinologica,
K Oishi, and
K Okada, and
O Yoshida, and
J C Romijn, and
J Bolt de Vries, and
F H Schröder
June 2001,
Steroids,
K Oishi, and
K Okada, and
O Yoshida, and
J C Romijn, and
J Bolt de Vries, and
F H Schröder
January 1997,
The Prostate,
K Oishi, and
K Okada, and
O Yoshida, and
J C Romijn, and
J Bolt de Vries, and
F H Schröder
January 1994,
Progress in clinical and biological research,
K Oishi, and
K Okada, and
O Yoshida, and
J C Romijn, and
J Bolt de Vries, and
F H Schröder
December 2004,
Annales d'urologie,
K Oishi, and
K Okada, and
O Yoshida, and
J C Romijn, and
J Bolt de Vries, and
F H Schröder
January 1985,
The Prostate,
K Oishi, and
K Okada, and
O Yoshida, and
J C Romijn, and
J Bolt de Vries, and
F H Schröder
September 1987,
Journal of steroid biochemistry,
