-transparent.png){kind=logo}
Dogs with liver disease have been shown to have increased serum C-reactive protein (CRP) concentrations. However, it is unclear whether dogs with liver disease also have increased serum haptoglobin concentrations. The aim of the study was to measure serum haptoglobin concentrations in healthy dogs, hospitalised dogs and dogs with liver diseases. Haptoglobin concentrations were measured in 30 healthy dogs, 47 hospitalised dogs with non-hepatic illness, 46 dogs with congenital portosystemic shunt (cPSS) and 11 dogs with primary hepatopathy. Haptoglobin concentrations were not significantly different between cPSS dogs with and without hepatic encephalopathy (HE), thus all cPSS dogs were considered as one group. Haptoglobin concentrations were significantly different between the remaining groups (P<0.0001). Hospitalised ill dogs had significantly higher haptoglobin concentrations than healthy dogs (P<0.001), dogs with cPSS (P<0.001) and dogs with primary hepatopathy (P<0.05). There was no significant difference between haptoglobin concentrations in healthy dogs, dogs with cPSS and dogs with primary hepatopathy. Haptoglobin concentrations were not significantly increased in dogs with liver diseases or in dogs with cPSS and HE. This is in contrast with the previously reported CRP results. This study demonstrates that liver function should be considered when interpreting haptoglobin concentrations in dogs.
K Crawford, and
S M Warman, and
A I Marques, and
D A Yool, and
P D Eckersall, and
E McCulloch, and
K Lynn, and
R J Mellanby, and
A G Gow
December 1961,
Gut,
K Crawford, and
S M Warman, and
A I Marques, and
D A Yool, and
P D Eckersall, and
E McCulloch, and
K Lynn, and
R J Mellanby, and
A G Gow
January 1986,
Veterinary clinical pathology,
K Crawford, and
S M Warman, and
A I Marques, and
D A Yool, and
P D Eckersall, and
E McCulloch, and
K Lynn, and
R J Mellanby, and
A G Gow
July 2012,
The Veterinary record,
K Crawford, and
S M Warman, and
A I Marques, and
D A Yool, and
P D Eckersall, and
E McCulloch, and
K Lynn, and
R J Mellanby, and
A G Gow
May 2021,
Journal of veterinary internal medicine,
K Crawford, and
S M Warman, and
A I Marques, and
D A Yool, and
P D Eckersall, and
E McCulloch, and
K Lynn, and
R J Mellanby, and
A G Gow
January 1987,
Veterinary pathology,
K Crawford, and
S M Warman, and
A I Marques, and
D A Yool, and
P D Eckersall, and
E McCulloch, and
K Lynn, and
R J Mellanby, and
A G Gow
January 2016,
Polish journal of veterinary sciences,
K Crawford, and
S M Warman, and
A I Marques, and
D A Yool, and
P D Eckersall, and
E McCulloch, and
K Lynn, and
R J Mellanby, and
A G Gow
July 1969,
Vox sanguinis,
K Crawford, and
S M Warman, and
A I Marques, and
D A Yool, and
P D Eckersall, and
E McCulloch, and
K Lynn, and
R J Mellanby, and
A G Gow
June 1986,
The Southeast Asian journal of tropical medicine and public health,
K Crawford, and
S M Warman, and
A I Marques, and
D A Yool, and
P D Eckersall, and
E McCulloch, and
K Lynn, and
R J Mellanby, and
A G Gow
February 1964,
Clinical science,
K Crawford, and
S M Warman, and
A I Marques, and
D A Yool, and
P D Eckersall, and
E McCulloch, and
K Lynn, and
R J Mellanby, and
A G Gow
December 2012,
American journal of veterinary research,
