Biomaterial Database

Chondrogenesis in peripheral fibromas of the gingiva. Histochemical demonstration of oxytalan fibers and mucopolysaccharides. 1986

K Balogh, and J Richardson

Five lesions were studied to elucidate the histogenesis of cartilage in peripheral fibromas. Cytological features suggested direct transformation from fibroblast-like cells to chondrocytes (cartilaginous metaplasia). Supportive evidence for such differentiation was the presence of neutral and acid mucopolysaccharides in the loose stroma of the lesions as well as in the ground substance of the cartilaginous centers. In one instance, the metaplastic cartilage showed bone formation. An increased number of oxytalan fibers could be demonstrated in the fibroma and in the cartilage.

UI	MeSH Term	Description	Entries
D002356	Cartilage	A non-vascular form of connective tissue composed of CHONDROCYTES embedded in a matrix that includes CHONDROITIN SULFATE and various types of FIBRILLAR COLLAGEN. There are three major types: HYALINE CARTILAGE; FIBROCARTILAGE; and ELASTIC CARTILAGE.	Cartilages
D003285	Contractile Proteins	Proteins which participate in contractile processes. They include MUSCLE PROTEINS as well as those found in other cells and tissues. In the latter, these proteins participate in localized contractile events in the cytoplasm, in motile activity, and in cell aggregation phenomena.	Contractile Protein,Protein, Contractile,Proteins, Contractile
D005350	Fibroma	A benign tumor of fibrous or fully developed connective tissue.	Fibromatosis,Fibromyxoma,Myxofibroma,Fibromas,Fibromatoses,Fibromyxomas,Myxofibromas
D005887	Gingival Neoplasms	New abnormal growth of tissue in the GINGIVA.	Epulis, Congenital,Congenital Epulides,Congenital Epulis,Epulides, Congenital,Neoplasms, Gingival,Gingival Neoplasm,Neoplasm, Gingival
D006025	Glycosaminoglycans	Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine (see ACETYLGLUCOSAMINE) or N-acetylgalactosamine (see ACETYLGALACTOSAMINE).	Glycosaminoglycan,Mucopolysaccharides
D006651	Histocytochemistry	Study of intracellular distribution of chemicals, reaction sites, enzymes, etc., by means of staining reactions, radioactive isotope uptake, selective metal distribution in electron microscopy, or other methods.	Cytochemistry
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000072260	RNA Splicing Factors	RNA-binding proteins that facilitate or inhibit RNA SPLICING.	Splicing Factor,Splicing Factors,Factor, Splicing,Factors, RNA Splicing,Factors, Splicing,Splicing Factors, RNA
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly