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The behavior of trypsin/creatinine clearance ratio (Ctr/Ccr) and serum immunoreactive trypsin (IRT) was evaluated in a total of 168 subjects with pancreatic cancer, chronic pancreatitis and non-pancreatic digestive diseases. Amylase/creatinine clearance ratio (Cam/Ccr) and serum amylase levels were also evaluated in order to establish their possible relationship with Ctr/Ccr and IRT values. Elevated Ctr/Ccr and IRT values were observed in several patients with pancreatic cancer and chronic pancreatitis. Abnormal IRT and Ctr/Ccr values were found in 28.2 and 4% of non-pancreatic digestive diseases, respectively. IRT and amylase serum levels showed consensual modifications, while Ctr/Ccr showed a behavior different from that of Cam/Ccr. Liver damage seems to play a role in increasing serum IRT levels of patients without pancreatic involvement, while the increased Ctr/Ccr seems to depend on other factors, for instance renal tubular dysfunction.
G Del Favero, and
C Fabris, and
P Bonvicini, and
A Piccoli, and
U Baccaglini, and
S Pedrazzoli, and
A Burlina, and
R Naccarato
July 1979,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
G Del Favero, and
C Fabris, and
P Bonvicini, and
A Piccoli, and
U Baccaglini, and
S Pedrazzoli, and
A Burlina, and
R Naccarato
October 1980,
Clinical chemistry,
G Del Favero, and
C Fabris, and
P Bonvicini, and
A Piccoli, and
U Baccaglini, and
S Pedrazzoli, and
A Burlina, and
R Naccarato
September 1983,
Research communications in chemical pathology and pharmacology,
G Del Favero, and
C Fabris, and
P Bonvicini, and
A Piccoli, and
U Baccaglini, and
S Pedrazzoli, and
A Burlina, and
R Naccarato
January 1989,
Annals of clinical biochemistry,
G Del Favero, and
C Fabris, and
P Bonvicini, and
A Piccoli, and
U Baccaglini, and
S Pedrazzoli, and
A Burlina, and
R Naccarato
July 1985,
European journal of pediatrics,
G Del Favero, and
C Fabris, and
P Bonvicini, and
A Piccoli, and
U Baccaglini, and
S Pedrazzoli, and
A Burlina, and
R Naccarato
January 1987,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
G Del Favero, and
C Fabris, and
P Bonvicini, and
A Piccoli, and
U Baccaglini, and
S Pedrazzoli, and
A Burlina, and
R Naccarato
May 1983,
Research communications in chemical pathology and pharmacology,
G Del Favero, and
C Fabris, and
P Bonvicini, and
A Piccoli, and
U Baccaglini, and
S Pedrazzoli, and
A Burlina, and
R Naccarato
November 1979,
Klinische Wochenschrift,
G Del Favero, and
C Fabris, and
P Bonvicini, and
A Piccoli, and
U Baccaglini, and
S Pedrazzoli, and
A Burlina, and
R Naccarato
May 1983,
Clinica chimica acta; international journal of clinical chemistry,
G Del Favero, and
C Fabris, and
P Bonvicini, and
A Piccoli, and
U Baccaglini, and
S Pedrazzoli, and
A Burlina, and
R Naccarato
June 1986,
Journal of clinical pathology,
