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The gramicidin S-producing organisms Bacillus brevis was grown under submerged conditions in fermenters at a temperature of 32 degrees C which is the lower limit of the temperature ranges providing the culture growth. The culture was also grown under the optimal temperature conditions, i.e. 40 degrees C. At the lower temperature the biomass synthesis at the early stage of the culture development was decreased, the intensity of the cell respiration was low and solubility of oxygen in the liquid was increased. Under such conditions the decrease in the levels of dissolved oxygen in the medium was less pronounced than that under the control conditions. At the lower temperature limitation of the culture growth by the deficit of dissolved oxygen lowered and the period of the antibiotic synthesis increased which brought about a rise of the gramicidin S yield by 30-40 per cent.
T P Udalova, and
V G Bulgakova, and
A N Polin, and
N S Egorov
September 1981,
Antibiotiki,
T P Udalova, and
V G Bulgakova, and
A N Polin, and
N S Egorov
September 1981,
Antibiotiki,
T P Udalova, and
V G Bulgakova, and
A N Polin, and
N S Egorov
January 1973,
Prikladnaia biokhimiia i mikrobiologiia,
T P Udalova, and
V G Bulgakova, and
A N Polin, and
N S Egorov
January 2003,
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic],
T P Udalova, and
V G Bulgakova, and
A N Polin, and
N S Egorov
January 1985,
Nauchnye doklady vysshei shkoly. Biologicheskie nauki,
T P Udalova, and
V G Bulgakova, and
A N Polin, and
N S Egorov
May 1982,
The Journal of antibiotics,
T P Udalova, and
V G Bulgakova, and
A N Polin, and
N S Egorov
November 1963,
Biochimica et biophysica acta,
T P Udalova, and
V G Bulgakova, and
A N Polin, and
N S Egorov
January 1976,
Mikrobiologiia,
T P Udalova, and
V G Bulgakova, and
A N Polin, and
N S Egorov
July 1976,
European journal of biochemistry,
T P Udalova, and
V G Bulgakova, and
A N Polin, and
N S Egorov
March 1985,
Journal of general microbiology,
