-transparent.png){kind=logo}
S-adenosyl-L-methionine: (S)-scoulerine 9-O-methyltransferase, a highly stereo- and regio-specific enzyme in tetrahydroprotoberberine biosynthesis. 1985
Lehrstuhl für Pharmazeutische Biologie der Universität München, Karlstrasse 29, D-8000, München 2, FRG.
Suspension cultures of Berberis species are useful sources for the detection and isolation of a new enzyme which transfers the methyl group from S-adenosyl-L-methionine specifically to the 9-position of the (S)-enantiomer of scoulerine, producing (S)-tetrahydrocolumbamine. The enzyme was enriched 27-fold; it is not particle bound, has a pH optimum of 8.9, a molecular weight of 63 000 and shows a high degree of substrate specificity.
| UI | MeSH Term | Description | Entries |
|---|
Related Publications
S Muemmler, and
M Rueffer, and
N Nagakura, and
M H Zenk
January 2010,
International review of neurobiology,
S Muemmler, and
M Rueffer, and
N Nagakura, and
M H Zenk
June 1986,
Plant cell reports,
S Muemmler, and
M Rueffer, and
N Nagakura, and
M H Zenk
October 1984,
Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire,
S Muemmler, and
M Rueffer, and
N Nagakura, and
M H Zenk
July 2018,
Nature communications,
S Muemmler, and
M Rueffer, and
N Nagakura, and
M H Zenk
September 1975,
Antimicrobial agents and chemotherapy,
S Muemmler, and
M Rueffer, and
N Nagakura, and
M H Zenk
February 2021,
Proteins,
S Muemmler, and
M Rueffer, and
N Nagakura, and
M H Zenk
March 1993,
Biochemistry,
S Muemmler, and
M Rueffer, and
N Nagakura, and
M H Zenk
January 2022,
Methods in enzymology,
S Muemmler, and
M Rueffer, and
N Nagakura, and
M H Zenk
December 1985,
Plant cell reports,
S Muemmler, and
M Rueffer, and
N Nagakura, and
M H Zenk
April 1984,
Journal of chromatography,
