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The study of the antigenic composition of hemagglutinins of influenza H3N2 viruses isolated during epidemic outbreaks in 1979-1983, carried out by means of monospecific antibodies to individual antigenic determinants, showed heterogeneity of the antigenic structure of epidemically active variants. Some variants were antigenically identical to A/Bangkok/1/79 virus. Hemagglutinin structure of A/Shanghai/31/80, A/Philippines/2/82 and the like was found to contain a qualitatively new antigenic determinant heretofore undetectable in H1N1, H3N2 viruses.
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