A new absorbable annuloplasty ring in the tricuspid position: an experimental study. 1986

C M Durán, and J M Revuelta, and F Val Bernal

An absorbable bovine fibrin annuloplasty ring was implanted in the tricuspid position in 30 adult mongrel dogs to determine the rate of absorption and the effectiveness of this new method of annuloplasty. There were 4 early deaths. The remaining 26 dogs survived the operation and were electively sacrificed. The cumulative follow-up was 111.5 months (14 days to one year). Mean follow-up was 4.2 months per animal. Six dogs sacrificed between 2 and 4 weeks (group I) showed mild to moderate ring surface erosion and a fibrinous capsule covering the prosthesis. Nine out of 10 specimens showed total absence of the ring 1 to 2 months after surgery (group II), and all bovine fibrin tissue had disappeared in the 10 remaining dogs after 2 months of implantation (group III). In 2 cases small areas of chondroid degeneration were detected 4 months after surgery. This concept of a time-controlled biodegradable annuloplasty might be useful, although further studies are needed before its clinical application.

UI MeSH Term Description Entries
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D006350 Heart Valve Prosthesis A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material. Prosthesis, Heart Valve,Cardiac Valve Prosthesis,Cardiac Valve Prostheses,Heart Valve Prostheses,Prostheses, Cardiac Valve,Prostheses, Heart Valve,Prosthesis, Cardiac Valve,Valve Prostheses, Cardiac,Valve Prostheses, Heart,Valve Prosthesis, Cardiac,Valve Prosthesis, Heart
D000042 Absorption The physical or physiological processes by which substances, tissue, cells, etc. take up or take in other substances or energy.
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001705 Bioprosthesis Prosthesis, usually heart valve, composed of biological material and whose durability depends upon the stability of the material after pretreatment, rather than regeneration by host cell ingrowth. Durability is achieved 1, mechanically by the interposition of a cloth, usually polytetrafluoroethylene, between the host and the graft, and 2, chemically by stabilization of the tissue by intermolecular linking, usually with glutaraldehyde, after removal of antigenic components, or the use of reconstituted and restructured biopolymers. Glutaraldehyde-Stabilized Grafts,Heterograft Bioprosthesis,Porcine Xenograft Bioprosthesis,Xenograft Bioprosthesis,Bioprostheses,Bioprostheses, Heterograft,Bioprostheses, Porcine Xenograft,Bioprostheses, Xenograft,Bioprosthesis, Heterograft,Bioprosthesis, Porcine Xenograft,Bioprosthesis, Xenograft,Glutaraldehyde Stabilized Grafts,Glutaraldehyde-Stabilized Graft,Graft, Glutaraldehyde-Stabilized,Grafts, Glutaraldehyde-Stabilized,Heterograft Bioprostheses,Porcine Xenograft Bioprostheses,Xenograft Bioprostheses,Xenograft Bioprostheses, Porcine,Xenograft Bioprosthesis, Porcine
D014261 Tricuspid Valve The valve consisting of three cusps situated between the right atrium and right ventricle of the heart. Tricuspid Valves,Valve, Tricuspid,Valves, Tricuspid

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