Biomaterial Database

The double collision technique: a new method for measurement of the motor nerve refractory period distribution in man. 1987

D A Ingram, and G R Davis, and M Swash

A new, double collision, technique is described for non-invasive measurement of the motor nerve refractory period distribution for human peripheral nerves. In contrast to previous collision techniques, this method is independent of the transient changes in nerve and muscle fibre conduction which can distort test muscle responses. The end-point of the distribution is determined by a null response; this permits accurate identification of those nerve fibres with the longest refractory periods. We have used the double collision technique to measure the refractory period distributions for the median nerve at the wrist in 20 normal subjects aged between 22 and 58 (mean 35) years. 150% maximal stimuli were used with a controlled limb temperature of 35 degrees C. Following a conditioning stimulus, the mean latencies for recovery of 5%, 50%, 95% and 99% of motor nerve fibres were 0.94, 1.03, 1.12 and 1.23 msec respectively. Data are also presented for the ulnar and peroneal nerves. The results show that the human motor nerve refractory period distribution is much less dispersed than has been previously supposed.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008475	Median Nerve	A major nerve of the upper extremity. In humans, the fibers of the median nerve originate in the lower cervical and upper thoracic spinal cord (usually C6 to T1), travel via the brachial plexus, and supply sensory and motor innervation to parts of the forearm and hand.	Median Nerves,Nerve, Median,Nerves, Median
D008722	Methods	A series of steps taken in order to conduct research.	Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009431	Neural Conduction	The propagation of the NERVE IMPULSE along the nerve away from the site of an excitation stimulus.	Nerve Conduction,Conduction, Nerve,Conduction, Neural,Conductions, Nerve,Conductions, Neural,Nerve Conductions,Neural Conductions
D010525	Peripheral Nerves	The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.	Endoneurium,Epineurium,Perineurium,Endoneuriums,Epineuriums,Nerve, Peripheral,Nerves, Peripheral,Perineuriums,Peripheral Nerve
D010543	Peroneal Nerve	The lateral of the two terminal branches of the sciatic nerve. The peroneal (or fibular) nerve provides motor and sensory innervation to parts of the leg and foot.	Fibular Nerve,Fibular Nerves,Nerve, Fibular,Nerve, Peroneal,Nerves, Fibular,Nerves, Peroneal,Peroneal Nerves
D004558	Electric Stimulation	Use of electric potential or currents to elicit biological responses.	Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D004569	Electroencephalography	Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.	EEG,Electroencephalogram,Electroencephalograms
D004594	Electrophysiology	The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.