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It was shown in Wistar male rats that the development of tourniquet shock was followed by an increase of proteolytic activity in the blood by 3 times, activity of aspartate aminotransferase (AST) by 3 times, that of alanine aminotransferase (ALT) by 6 times, contents of urea and residual nitrogen by 2.5-3 times; level of alpha 1-protease inhibitor (alpha 1-PI) decreased by 4 times and that of alpha 2-macroglobulin (alpha 2MG) by 2.5 times. At administration of contrykal (10,000 U/kg) proteolytic activity increased only by 32.5%, content of alpha 1-PI decreased only by 10-20% and level of alpha 2-MG did not differ from that in healthy animals. Activity of AST and ALT remained high, and contents of urea and residual nitrogen were near-normal.
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V A Protsenko, and
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Klinichna khirurhiia,
V A Protsenko, and
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V A Protsenko, and
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Biulleten' eksperimental'noi biologii i meditsiny,
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October 1998,
Biulleten' eksperimental'noi biologii i meditsiny,
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Biulleten' eksperimental'noi biologii i meditsiny,
