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The nature of the epidermal cellular infiltrate in pagetoid reticulosis is still subject to intense controversies. Using a panel of recently developed monoclonal antibodies against cell activation and proliferation associated antigens it was possible to demonstrate the activated state of numerous T cells within the lesional epidermis. Moreover approximately 10% of these T cells reacted with proliferation associated antigens. In addition macrophages and Langerhans' cells were found to represent a regular constituent of the epidermal infiltrate with a density clearly exceeding that of unaffected adjacent epidermis. The close apposition of activated T cells and monocytic cells suggests an intensive interaction of both cell types in the development of the pagetoid reticulosis lesion.
P Kaudewitz, and
G Burg, and
G Majiewski, and
J Gerdes, and
R Schwarting, and
O Braun-Falco
January 1984,
Acta dermato-venereologica,
P Kaudewitz, and
G Burg, and
G Majiewski, and
J Gerdes, and
R Schwarting, and
O Braun-Falco
May 1986,
Journal of the American Academy of Dermatology,
P Kaudewitz, and
G Burg, and
G Majiewski, and
J Gerdes, and
R Schwarting, and
O Braun-Falco
January 1984,
Dermatologica,
P Kaudewitz, and
G Burg, and
G Majiewski, and
J Gerdes, and
R Schwarting, and
O Braun-Falco
May 1982,
Acta pathologica japonica,
P Kaudewitz, and
G Burg, and
G Majiewski, and
J Gerdes, and
R Schwarting, and
O Braun-Falco
August 1984,
The British journal of dermatology,
P Kaudewitz, and
G Burg, and
G Majiewski, and
J Gerdes, and
R Schwarting, and
O Braun-Falco
January 1984,
Uremia investigation,
P Kaudewitz, and
G Burg, and
G Majiewski, and
J Gerdes, and
R Schwarting, and
O Braun-Falco
May 2000,
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc,
P Kaudewitz, and
G Burg, and
G Majiewski, and
J Gerdes, and
R Schwarting, and
O Braun-Falco
December 2013,
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG,
P Kaudewitz, and
G Burg, and
G Majiewski, and
J Gerdes, and
R Schwarting, and
O Braun-Falco
July 2016,
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc,
P Kaudewitz, and
G Burg, and
G Majiewski, and
J Gerdes, and
R Schwarting, and
O Braun-Falco
January 1986,
Acta clinica Belgica,
