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Extramedullary blast crisis of chronic myelogenous leukemia as an initial presentation. 2013
Shokichi Tsukamoto, and
Satoshi Ota, and
Chikako Ohwada, and
Yusuke Takeda, and
Masahiro Takeuchi, and
Emiko Sakaida, and
Naomi Shimizu, and
Koutaro Yokote, and
Tohru Iseki, and
Chiaki Nakaseko
Department of Hematology, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan.
Extramedullary blast crisis of chronic myelogenous leukemia (CML) is defined as the development of extramedullary disease caused by the infiltration of blasts regardless of proliferation of blasts in the bone marrow. The onset of extramedullary blast crisis in the newly diagnosed patients is known to be extremely rare. Here, we present a case of extramedullary blast crisis of CML as an initial presentation in a 17-year-old female presenting with pain in the left femur tumor. This case was treated successfully with dasatinib and allogeneic hematopoietic stem cell transplantation, with achievement of long-term remission.
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