A case of EBV positive diffuse large B-cell lymphoma of the adolescent. 2014

Qilin Ao, and Ying Wang, and Sanpeng Xu, and Ye Tian, and Wei Huang
Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Da Dao, Wuhan 430030, P. R. China.

EBV positive diffuse large B-cell lymphoma (DLBCL) can happen to the elderly, seldom to the young. The case of EBV positive DLBCL has rarely been reported in the adolescent. We report a rare case of EBV positive DLBCL in a 17-year-old man with normal immune state. He was diagnosed by morphology, immunohistochemistry, in situ hybridization for EBV, Flow cytometer, IG/TCR gene rearrangement and cytogenetic study. The occurrence of this case suggests that EBV-positive DLBCL can happen to adolescent patients with normal immune state and cytogenetic study takes an important role in the diagnosis of adolescent EBV-positive DLBCL.

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