Draft genome sequence of Francisella tularensis subsp. holarctica BD11-00177. 2013

Jordy P M Coolen, and Andreas Sjödin, and Boulos Maraha, and Gerard F Hajer, and Mats Forsman, and Ellen Verspui, and Hendrina M E Frenay, and Daan W Notermans, and Maaike C de Vries, and Frans A G Reubsaet, and Armand Paauw, and Guus Roeselers
TNO, The Netherlands.

Francisella tularensis is a facultative intracellular bacterium in the class Gammaproteobacteria. This strain is of interest because it is the etiologic agent of tularemia and a highly virulent category A biothreat agent. Here we describe the draft genome sequence and annotation of Francisella tularensis subsp. holarctica BD11-00177, isolated from the first case of indigenous tularemia detected in The Netherlands since 1953. Whole genome DNA sequence analysis assigned this isolate to the genomic group B.FTNF002-00, which previously has been exclusively reported from Spain, France, Italy, Switzerland and Germany. Automatic annotation of the 1,813,372 bp draft genome revealed 2,103 protein-coding and 46 RNA genes.

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