Biomaterial Database

Hendersonula toruloidea infection: successful response of onychomycosis to nail avulsion and topical ciclopiroxolamine. 1987

O Rollman, and S Johansson

Department of Dermatology, University of Uppsala, Sweden.

The exotic mould Hendersonula toruloidea may occasionally produce a ringwormlike, non-inflammatory, therapy-resistant mycosis of the skin and nails simulating chronic dermatophytosis. We report on a 30-year-old Nigerian male who, after two years' sojourn in Sweden, developed finger-nail dystrophy and mild scaling of the palm and sole skin due to H. toruloidea infection. Nail avulsion followed by long-term occlusive application of ciclopiroxolamine cleared the onychomycosis, whereas the sole and palm infection was resistant to ciclopiroxolamine and glutaraldehyde treatment.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009262	Nails	The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates.	Fingernails,Toenails,Fingernail,Nail,Toenail
D011728	Pyridones	Pyridine derivatives with one or more keto groups on the ring.	Pyridinones
D003904	Mitosporic Fungi	A large and heterogenous group of fungi whose common characteristic is the absence of a sexual state. Many of the pathogenic fungi in humans belong to this group.	Deuteromycetes,Deuteromycota,Fungi imperfecti,Fungi, Mitosporic,Hyphomycetes,Deuteromycete,Deuteromycotas,Fungi imperfectus,Fungus, Mitosporic,Hyphomycete,Mitosporic Fungus,imperfectus, Fungi
D006229	Hand Dermatoses	Skin diseases involving the HANDS.	Hand Dermatosis,Dermatoses, Hand,Dermatosis, Hand
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000077768	Ciclopirox	A cyclohexane and pyridinone derivative that is used for the treatment of fungal infections of the skin and nails, and for treatment of VAGINAL YEAST INFECTIONS.	6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone ethanolamine salt,Batrafen,Ciclopirox Olamine,Ciclopiroxolamine,Cyclopirox,Cyclopyroxolamine,Dafnegin-CSC,HOE 296,HOE-296,Loprox,Penlac,Dafnegin CSC,HOE296
D000279	Administration, Cutaneous	The application of suitable drug dosage forms to the skin for either local or systemic effects.	Cutaneous Drug Administration,Dermal Drug Administration,Drug Administration, Dermal,Percutaneous Administration,Skin Drug Administration,Transcutaneous Administration,Transdermal Administration,Administration, Dermal,Administration, Transcutaneous,Administration, Transdermal,Cutaneous Administration,Cutaneous Administration, Drug,Dermal Administration,Drug Administration, Cutaneous,Skin Administration, Drug,Administration, Cutaneous Drug,Administration, Dermal Drug,Administration, Percutaneous,Administrations, Cutaneous,Administrations, Cutaneous Drug,Administrations, Dermal,Administrations, Dermal Drug,Administrations, Percutaneous,Administrations, Transcutaneous,Administrations, Transdermal,Cutaneous Administrations,Cutaneous Administrations, Drug,Cutaneous Drug Administrations,Dermal Administrations,Dermal Drug Administrations,Drug Administrations, Cutaneous,Drug Administrations, Dermal,Drug Skin Administrations,Percutaneous Administrations,Skin Administrations, Drug,Skin Drug Administrations,Transcutaneous Administrations,Transdermal Administrations
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000935	Antifungal Agents	Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.	Anti-Fungal Agents,Antifungal Agent,Fungicides, Therapeutic,Antibiotics, Antifungal,Therapeutic Fungicides,Agent, Antifungal,Anti Fungal Agents,Antifungal Antibiotics