Head trauma is a leading cause of disability and death in young adults in the United States and elsewhere [1-4]. It has been estimated that 422000 patients are hospitalized annually in the United States for head injury [5]. Closed (non-penetrating) head injury accounts for the vast majority of civilian head injuries [6], the major causes of which are motor vehicle accidents (50%) and domestic accidents or falls (33%) [3,5,7]. The majority of victims of head injury will survive, but a large number suffer from significant medical, psychological and neurological sequelae, including seizures. In this chapter we review the literature concerning the relationship of posttraumatic seizures and posttraumatic epilepsy to rehabilitation outcomes following closed head injury.