BIOMAT Database Logo BIOMAT Database Logo

Agreement between colposcopic diagnosis and cervical pathology: Siriraj hospital experience. 2014

Molpen Tatiyachonwiphut, and Atthapon Jaishuen, and Suthi Sangkarat, and Somsak Laiwejpithaya, and Weerasak Wongtiraporn, and Perapong Inthasorn, and Boonlert Viriyapak, and Malee Warnnissorn
Department of Obstetrics and Gynaecology, Gynaecologic Oncology Unit, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand E-mail : suthi.san@mahidol.ac.th.

OBJECTIVE To evaluate the agreement between colposcopic diagnosis and cervical pathology a retrospective chart review was performed. METHODS This study included 437 patients who underwent colposcopy and cervical biopsy or conization at Siriraj Hospital from October 2010 - December 2012. The patient clinical characteristics, cervical cytology results, colposcopic diagnoses, cervical pathology results were recorded and correlations between variables were analyzed. RESULTS Agreement of colposcopic diagnosis and cervical pathology was matched in 253 patients (57.9%). The strength of agreement with weighted Kappa statistic was 0.494 (p<0.001). Colposcopic diagnoses more often overestimated (31.1%) than underestimated (11%) the cervical pathology. Agreement of colposcopic diagnosis and cervical pathology within 1 grade was found in 411 patients (94.1%). Positive predictive value (PPV) of high grade colposcopy or more was 75.5%, whereas the negative predictive value (NPV) of insignificant and low grade colposcopy was 83.8%. False positives of high grade colposcopy or more were 21%. False negatives of insignificant or low grade colposcopy were 19.1%. CONCLUSIONS Strength of agreement between colposcopic diagnosis and cervical pathology was found to be only moderate. A biopsy at colposcopy should be performed at a gold standard level to detect high grade lesions.

UI MeSH Term Description Entries
D008679 Metaplasia A condition in which there is a change of one adult cell type to another similar adult cell type.
D011127 Polyps Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base. Polyp
D011237 Predictive Value of Tests In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test. Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D002575 Uterine Cervicitis Inflammation of the UTERINE CERVIX. Cervicitis,Cervicitides,Cervicitides, Uterine,Cervicitis, Uterine,Uterine Cervicitides
D002578 Uterine Cervical Dysplasia Abnormal development of immature squamous EPITHELIAL CELLS of the UTERINE CERVIX, a term used to describe premalignant cytological changes in the cervical EPITHELIUM. These atypical cells do not penetrate the epithelial BASEMENT MEMBRANE. Cervical Dysplasia,Cervical Intraepithelial Neoplasia,Cervix Dysplasia,Dysplasia of Cervix Uteri,Neoplasia, Cervical Intraepithelial,Cervical Intraepithelial Neoplasia, Grade III,Cervical Intraepithelial Neoplasms,Intraepithelial Neoplasia, Cervical,Cervical Dysplasia, Uterine,Cervical Dysplasias,Cervical Intraepithelial Neoplasm,Cervix Uteri Dysplasia,Cervix Uteri Dysplasias,Dysplasia, Cervical,Dysplasia, Cervix,Dysplasia, Uterine Cervical,Intraepithelial Neoplasm, Cervical,Intraepithelial Neoplasms, Cervical,Neoplasm, Cervical Intraepithelial,Neoplasms, Cervical Intraepithelial
D002583 Uterine Cervical Neoplasms Tumors or cancer of the UTERINE CERVIX. Cancer of Cervix,Cancer of the Cervix,Cancer of the Uterine Cervix,Cervical Cancer,Cervical Neoplasms,Cervix Cancer,Cervix Neoplasms,Neoplasms, Cervical,Neoplasms, Cervix,Uterine Cervical Cancer,Cancer, Cervical,Cancer, Cervix,Cancer, Uterine Cervical,Cervical Cancer, Uterine,Cervical Cancers,Cervical Neoplasm,Cervical Neoplasm, Uterine,Cervix Neoplasm,Neoplasm, Cervix,Neoplasm, Uterine Cervical,Uterine Cervical Cancers,Uterine Cervical Neoplasm
D002584 Cervix Uteri The neck portion of the UTERUS between the lower isthmus and the VAGINA forming the cervical canal. Cervical Canal of the Uterus,Cervical Canal, Uterine,Ectocervix,Endocervical Canal,Endocervix,External Os Cervix,External Os of the Cervix,Uterine Cervical Canal,Cervix,Cervixes,Uterine Cervix,Canal, Endocervical,Canal, Uterine Cervical,Cervix, External Os,Cervix, Uterine,Endocervical Canals,Uterine Cervical Canals
D003127 Colposcopy The examination, therapy or surgery of the cervix and vagina by means of a specially designed endoscope introduced vaginally. Colposcopic Surgical Procedures,Surgical Procedures, Colposcopic,Colposcopic Surgery,Surgery, Colposcopic,Colposcopic Surgeries,Colposcopic Surgical Procedure,Colposcopies,Procedure, Colposcopic Surgical,Procedures, Colposcopic Surgical,Surgeries, Colposcopic,Surgical Procedure, Colposcopic
D005188 False Negative Reactions Negative test results in subjects who possess the attribute for which the test is conducted. The labeling of diseased persons as healthy when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed) False Negative Reaction,Reaction, False Negative,Reactions, False Negative
D005189 False Positive Reactions Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed) False Positive Reaction,Positive Reaction, False,Positive Reactions, False,Reaction, False Positive,Reactions, False Positive

Related Publications

Molpen Tatiyachonwiphut, and Atthapon Jaishuen, and Suthi Sangkarat, and Somsak Laiwejpithaya, and Weerasak Wongtiraporn, and Perapong Inthasorn, and Boonlert Viriyapak, and Malee Warnnissorn
[Agreement between colposcopic diagnosis with 2011 international terminology of colposcopy and cervical pathology in cervical lesions].
May 2015, Zhonghua fu chan ke za zhi,
Molpen Tatiyachonwiphut, and Atthapon Jaishuen, and Suthi Sangkarat, and Somsak Laiwejpithaya, and Weerasak Wongtiraporn, and Perapong Inthasorn, and Boonlert Viriyapak, and Malee Warnnissorn
[Preliminary experience with colposcopic diagnosis of cervical adenocarcinoma].
May 1993, Zhonghua zhong liu za zhi [Chinese journal of oncology],
Molpen Tatiyachonwiphut, and Atthapon Jaishuen, and Suthi Sangkarat, and Somsak Laiwejpithaya, and Weerasak Wongtiraporn, and Perapong Inthasorn, and Boonlert Viriyapak, and Malee Warnnissorn
Colposcopic evaluation of cervical pathology.
January 1979, Rocky Mountain medical journal,
Molpen Tatiyachonwiphut, and Atthapon Jaishuen, and Suthi Sangkarat, and Somsak Laiwejpithaya, and Weerasak Wongtiraporn, and Perapong Inthasorn, and Boonlert Viriyapak, and Malee Warnnissorn
[Consistency of diagnosis between cervical cytology and colposcopic biopsy diagnosis].
June 2018, Zhonghua bing li xue za zhi = Chinese journal of pathology,
Molpen Tatiyachonwiphut, and Atthapon Jaishuen, and Suthi Sangkarat, and Somsak Laiwejpithaya, and Weerasak Wongtiraporn, and Perapong Inthasorn, and Boonlert Viriyapak, and Malee Warnnissorn
Colposcopic diagnosis of cervical neoplasia.
February 1973, Obstetrics and gynecology,
Molpen Tatiyachonwiphut, and Atthapon Jaishuen, and Suthi Sangkarat, and Somsak Laiwejpithaya, and Weerasak Wongtiraporn, and Perapong Inthasorn, and Boonlert Viriyapak, and Malee Warnnissorn
Colposcopic diagnosis of cervical neoplasia.
October 1983, Singapore medical journal,
Molpen Tatiyachonwiphut, and Atthapon Jaishuen, and Suthi Sangkarat, and Somsak Laiwejpithaya, and Weerasak Wongtiraporn, and Perapong Inthasorn, and Boonlert Viriyapak, and Malee Warnnissorn
Pediatric kidney transplantation: Siriraj Hospital experience.
August 2001, Journal of the Medical Association of Thailand = Chotmaihet thangphaet,
Molpen Tatiyachonwiphut, and Atthapon Jaishuen, and Suthi Sangkarat, and Somsak Laiwejpithaya, and Weerasak Wongtiraporn, and Perapong Inthasorn, and Boonlert Viriyapak, and Malee Warnnissorn
Laser bronchoscopy: experience at Siriraj Hospital.
December 2001, Journal of the Medical Association of Thailand = Chotmaihet thangphaet,
Molpen Tatiyachonwiphut, and Atthapon Jaishuen, and Suthi Sangkarat, and Somsak Laiwejpithaya, and Weerasak Wongtiraporn, and Perapong Inthasorn, and Boonlert Viriyapak, and Malee Warnnissorn
Analysis of the agreement between colposcopic impression and histopathological diagnosis of cervical biopsy in a single tertiary center of Chengdu.
October 2021, Archives of gynecology and obstetrics,
Molpen Tatiyachonwiphut, and Atthapon Jaishuen, and Suthi Sangkarat, and Somsak Laiwejpithaya, and Weerasak Wongtiraporn, and Perapong Inthasorn, and Boonlert Viriyapak, and Malee Warnnissorn
[Colposcopic diagnosis of latent cervical cancer].
January 1950, Zentralblatt fur Gynakologie,
Copied contents to your clipboard!