Use of synergism to increase the sensitivity of a microbiological method for the assay of viomycin.
1952
W E DYE, and
H P LYNCH, and
T M CULLEN, and
E M SPRAGUE
UI
MeSH Term
Description
Entries
D004347
Drug Interactions
The action of a drug that may affect the activity, metabolism, or toxicity of another drug.
Drug Interaction,Interaction, Drug,Interactions, Drug
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001681
Biological Assay
A method of measuring the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. It includes virulence studies in animal fetuses in utero, mouse convulsion bioassay of insulin, quantitation of tumor-initiator systems in mouse skin, calculation of potentiating effects of a hormonal factor in an isolated strip of contracting stomach muscle, etc.
A strongly basic peptide, antibiotic complex from several strains of Streptomyces. It is allergenic and toxic to kidneys and the labyrinth. Viomycin is used in tuberculosis as several different salts and in combination with other agents.