Safety and efficacy of sequential transcatheter arterial chemoembolization and portal vein embolization prior to major hepatectomy for patients with HCC. 2014

Chuan Xu, and Peng-Hua Lv, and Xin-En Huang, and Shu-Xiang Wang, and Ling Sun, and Fu-An Wang, and Li-Fu Wang
Department of Interventional Radiology, Subei People Hospital of Jiangsu Province, Clinical Hospital of Yangzhou University, Yangzhou, China E-mail : whycn7@sina.com, huangxinen06@aliyun.com.

OBJECTIVE To evaluate the safety and efficacy of sequential transcatheter arterial chemoembolization (TACE )and portal vein embolization (PVE) before major hepatectomy for patients with hepatocellur carcinoma (HCC). METHODS In this retrospective case-control study, data were collected from patients who underwent sequential TACE and PVE prior to major hemihepactectomy. Liver volumes were measured by computed tomography volumetry before TACE, and preoperation to assess degree of future remnant liver (FRL) hypertrophy and to check whether intro- or extrohepatic metastasis existed. Liver function was monitored by biochemistry after TACE, prior to and after major hepatectomy. RESULTS Mean average FRL volume increased 32.3-71.4% (mean 55.4%) compared with preoperative FRL volume. After TACE, liver enzymes were elevated, but returned to normal in four weeks. During PVE and resection, no patient had intro- or extrohepatic metastasis. CONCLUSIONS Sequential TACE and PVE is an effective method to improve resection opportunity, expand the scope of surgical resection, and greatly reduce postoperative intra- and extrahepatic metastasis.

UI MeSH Term Description Entries
D007261 Infusions, Intra-Arterial Regional infusion of drugs via an arterial catheter. Often a pump is used to impel the drug through the catheter. Used in therapy of cancer, upper gastrointestinal hemorrhage, infection, and peripheral vascular disease. Infusions, Regional Arterial,Infusions, Intra Arterial,Infusions, Intraarterial,Arterial Infusion, Intra,Arterial Infusion, Regional,Arterial Infusions, Intra,Arterial Infusions, Regional,Infusion, Intra Arterial,Infusion, Intra-Arterial,Infusion, Intraarterial,Infusion, Regional Arterial,Intra Arterial Infusion,Intra Arterial Infusions,Intra-Arterial Infusion,Intra-Arterial Infusions,Intraarterial Infusion,Intraarterial Infusions,Regional Arterial Infusion,Regional Arterial Infusions
D008113 Liver Neoplasms Tumors or cancer of the LIVER. Cancer of Liver,Hepatic Cancer,Liver Cancer,Cancer of the Liver,Cancer, Hepatocellular,Hepatic Neoplasms,Hepatocellular Cancer,Neoplasms, Hepatic,Neoplasms, Liver,Cancer, Hepatic,Cancer, Liver,Cancers, Hepatic,Cancers, Hepatocellular,Cancers, Liver,Hepatic Cancers,Hepatic Neoplasm,Hepatocellular Cancers,Liver Cancers,Liver Neoplasm,Neoplasm, Hepatic,Neoplasm, Liver
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009367 Neoplasm Staging Methods which attempt to express in replicable terms the extent of the neoplasm in the patient. Cancer Staging,Staging, Neoplasm,Tumor Staging,TNM Classification,TNM Staging,TNM Staging System,Classification, TNM,Classifications, TNM,Staging System, TNM,Staging Systems, TNM,Staging, Cancer,Staging, TNM,Staging, Tumor,System, TNM Staging,Systems, TNM Staging,TNM Classifications,TNM Staging Systems
D011169 Portal Vein A short thick vein formed by union of the superior mesenteric vein and the splenic vein. Portal Veins,Vein, Portal,Veins, Portal
D011300 Preoperative Care Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed) Care, Preoperative,Preoperative Procedure,Preoperative Procedures,Procedure, Preoperative,Procedures, Preoperative
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D002404 Catheterization Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions. Cannulation,Cannulations,Catheterizations
D003131 Combined Modality Therapy The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used. Multimodal Treatment,Therapy, Combined Modality,Combined Modality Therapies,Modality Therapies, Combined,Modality Therapy, Combined,Multimodal Treatments,Therapies, Combined Modality,Treatment, Multimodal,Treatments, Multimodal

Related Publications

Chuan Xu, and Peng-Hua Lv, and Xin-En Huang, and Shu-Xiang Wang, and Ling Sun, and Fu-An Wang, and Li-Fu Wang
May 2011, Annals of surgical oncology,
Chuan Xu, and Peng-Hua Lv, and Xin-En Huang, and Shu-Xiang Wang, and Ling Sun, and Fu-An Wang, and Li-Fu Wang
August 2020, World journal of gastroenterology,
Chuan Xu, and Peng-Hua Lv, and Xin-En Huang, and Shu-Xiang Wang, and Ling Sun, and Fu-An Wang, and Li-Fu Wang
May 2015, Korean journal of hepato-biliary-pancreatic surgery,
Chuan Xu, and Peng-Hua Lv, and Xin-En Huang, and Shu-Xiang Wang, and Ling Sun, and Fu-An Wang, and Li-Fu Wang
January 2021, Zeitschrift fur Gastroenterologie,
Chuan Xu, and Peng-Hua Lv, and Xin-En Huang, and Shu-Xiang Wang, and Ling Sun, and Fu-An Wang, and Li-Fu Wang
June 2020, Hepatobiliary & pancreatic diseases international : HBPD INT,
Chuan Xu, and Peng-Hua Lv, and Xin-En Huang, and Shu-Xiang Wang, and Ling Sun, and Fu-An Wang, and Li-Fu Wang
October 2023, Updates in surgery,
Chuan Xu, and Peng-Hua Lv, and Xin-En Huang, and Shu-Xiang Wang, and Ling Sun, and Fu-An Wang, and Li-Fu Wang
September 2009, American journal of surgery,
Chuan Xu, and Peng-Hua Lv, and Xin-En Huang, and Shu-Xiang Wang, and Ling Sun, and Fu-An Wang, and Li-Fu Wang
December 2023, Updates in surgery,
Chuan Xu, and Peng-Hua Lv, and Xin-En Huang, and Shu-Xiang Wang, and Ling Sun, and Fu-An Wang, and Li-Fu Wang
June 2008, Seminars in interventional radiology,
Copied contents to your clipboard!