Biomaterial Database

Resolution of idiopathic granulomatous orbital inflammation with intraorbital triamcinolone. 2014

Elizabeth M McElnea, and Sean Hynes, and Gerry T Fahy

Department of Ophthalmology, University College Hospital Galway, Galway, Ireland.

A 77-year-old man presented with a right lower eyelid swelling. Biopsy and histopathology of the lesion identified idiopathic granulomatous orbital inflammation. Clinical resolution of this patient's orbital mass was achieved with injection of 40 mg triamcinolone acetonide, perilesionally, at three sites in the right orbit. Such treatment may thus form an alternative to oral corticosteroid therapy in the management of granulomatous orbital inflammation.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D005938	Glucocorticoids	A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.	Glucocorticoid,Glucocorticoid Effect,Glucorticoid Effects,Effect, Glucocorticoid,Effects, Glucorticoid
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D014221	Triamcinolone	A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. (From Martindale, The Extra Pharmacopoeia, 30th ed, p739)	Aristocort,Volon
D016727	Orbital Pseudotumor	A nonspecific tumor-like inflammatory lesion in the ORBIT of the eye. It is usually composed of mature LYMPHOCYTES; PLASMA CELLS; MACROPHAGES; LEUKOCYTES with varying degrees of FIBROSIS. Orbital pseudotumors are often associated with inflammation of the extraocular muscles (ORBITAL MYOSITIS) or inflammation of the lacrimal glands (DACRYOADENITIS).	Inflammatory Pseudotumor, Orbital,Granuloma, Plasma Cell, Orbital,Inflammatory Pseudotumor of Orbit,Orbital Granuloma, Plasma Cell,Orbital Inflammatory Pseudotumor,Plasma Cell Granuloma, Orbital,Pseudotumor, Inflammatory, Orbital,Inflammatory Pseudotumors, Orbital,Orbital Inflammatory Pseudotumors,Orbital Pseudotumors,Pseudotumor, Orbital,Pseudotumor, Orbital Inflammatory,Pseudotumors, Orbital