-transparent.png){kind=logo}
Peptidoleukotriene C4 (LTC4) and leukotriene B4 (LTB4) are both suspected of being inflammatory mediators and epidermal mitogenic agents in cutaneous psoriatic lesions. In the present study an LTC4 specific binding site was characterized in membranes from cultured human keratinocytes (Kd, 8.7 nmol/l; Bmax, 1.2 pmol/mg protein). In contrast LTB4 did not show any high affinity binding which could account for its biological effects. These data suggest that LTC4, unlike LTB4, acts on epidermal cells through a receptor-mediated mechanism.
Related Publications
A Muller, and
L Michel, and
N Basset-Seguin, and
G Modat, and
L Dubertret, and
C Bonne
June 1984,
Prostaglandins,
A Muller, and
L Michel, and
N Basset-Seguin, and
G Modat, and
L Dubertret, and
C Bonne
September 1987,
The Journal of pharmacology and experimental therapeutics,
A Muller, and
L Michel, and
N Basset-Seguin, and
G Modat, and
L Dubertret, and
C Bonne
August 1985,
Biochemical pharmacology,
A Muller, and
L Michel, and
N Basset-Seguin, and
G Modat, and
L Dubertret, and
C Bonne
February 1989,
European journal of pharmacology,
A Muller, and
L Michel, and
N Basset-Seguin, and
G Modat, and
L Dubertret, and
C Bonne
August 1987,
European journal of pharmacology,
A Muller, and
L Michel, and
N Basset-Seguin, and
G Modat, and
L Dubertret, and
C Bonne
April 1992,
The Journal of experimental zoology,
A Muller, and
L Michel, and
N Basset-Seguin, and
G Modat, and
L Dubertret, and
C Bonne
March 1987,
Prostaglandins, leukotrienes, and medicine,
A Muller, and
L Michel, and
N Basset-Seguin, and
G Modat, and
L Dubertret, and
C Bonne
March 1986,
European journal of pharmacology,
A Muller, and
L Michel, and
N Basset-Seguin, and
G Modat, and
L Dubertret, and
C Bonne
January 1986,
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie,
A Muller, and
L Michel, and
N Basset-Seguin, and
G Modat, and
L Dubertret, and
C Bonne
January 1988,
The Journal of clinical endocrinology and metabolism,
