-transparent.png){kind=logo}
Pancreatic secretory trypsin inhibitor (PSTI) is a specific trypsin inhibitor secreted by the acinar cells of the pancreas. Serum levels of immunoreactive PSTI have been reported elevated in patients with various malignancies including gynecologic tumors. The immunohistochemical localization of PSTI is studied in the comparison with argyrophilia and amylase immunoreactivity on 100 ovarian tumors, 35 endometrial carcinomas, and 34 cervical carcinomas. PSTI was noted in 19 of 85 common epithelial tumors of the ovary, being most frequently in mucinous tumors and less in endometrioid, but only occurred in immature pancreatic tissue of 1 of 15 germ cell tumors tested. In the uterus, 5 of 19 adenocarcinomas of the endometrium and 3 of 10 adenocarcinomas of the cervix were positive for PSTI immunoreactivity. PSTI was found more frequently in the tumors with argyrophil cells, especially of type I, but was related to the intestinal metaplasia and exocrine secretion rather than argyrophilia itself, judging from the different localization of PSTI and argyrophilic granules. No relationship was observed between amylase and PSTI immunoreactivity.
G Ueda, and
C Shimizu, and
Y Tanaka, and
M Inoue, and
O Tanizawa, and
M Ogawa, and
T Mori
January 2000,
Cancer detection and prevention,
G Ueda, and
C Shimizu, and
Y Tanaka, and
M Inoue, and
O Tanizawa, and
M Ogawa, and
T Mori
November 1990,
Journal of clinical pathology,
G Ueda, and
C Shimizu, and
Y Tanaka, and
M Inoue, and
O Tanizawa, and
M Ogawa, and
T Mori
December 1984,
Nihon Gan Chiryo Gakkai shi,
G Ueda, and
C Shimizu, and
Y Tanaka, and
M Inoue, and
O Tanizawa, and
M Ogawa, and
T Mori
January 1990,
American journal of clinical pathology,
G Ueda, and
C Shimizu, and
Y Tanaka, and
M Inoue, and
O Tanizawa, and
M Ogawa, and
T Mori
February 1995,
Nihon rinsho. Japanese journal of clinical medicine,
G Ueda, and
C Shimizu, and
Y Tanaka, and
M Inoue, and
O Tanizawa, and
M Ogawa, and
T Mori
January 1976,
Methods in enzymology,
G Ueda, and
C Shimizu, and
Y Tanaka, and
M Inoue, and
O Tanizawa, and
M Ogawa, and
T Mori
November 2004,
Nihon rinsho. Japanese journal of clinical medicine,
G Ueda, and
C Shimizu, and
Y Tanaka, and
M Inoue, and
O Tanizawa, and
M Ogawa, and
T Mori
August 1999,
Nihon rinsho. Japanese journal of clinical medicine,
G Ueda, and
C Shimizu, and
Y Tanaka, and
M Inoue, and
O Tanizawa, and
M Ogawa, and
T Mori
June 2010,
World journal of gastrointestinal pathophysiology,
G Ueda, and
C Shimizu, and
Y Tanaka, and
M Inoue, and
O Tanizawa, and
M Ogawa, and
T Mori
January 1988,
Advances in experimental medicine and biology,
