Improved histology from inadequately fixed paraffin-embedded biopsy specimens. 1989

J T Woosley
Department of Pathology, University of North Carolina, School of Medicine, Chapel Hill.

The rapid turnaround time demanded of many surgical pathology laboratories often results in the paraffin embedding of biopsy specimens that are less than optimally fixed. Occasionally, the quality of the resulting hematoxylin-and-eosin-stained sections is inadequate to provide a diagnosis. A method is described herein that permits the preparation of histologic sections of excellent quality from suboptimally fixed paraffin-embedded tissue.

UI MeSH Term Description Entries
D008198 Lymph Nodes They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system. Lymph Node,Node, Lymph,Nodes, Lymph
D006652 Histological Techniques Methods of preparing tissue for examination and study of the origin, structure, function, or pathology. Histologic Technic,Histologic Technics,Histologic Technique,Histologic Techniques,Histological Technics,Technic, Histologic,Technics, Histologic,Technique, Histologic,Techniques, Histologic,Histological Technic,Histological Technique,Technic, Histological,Technics, Histological,Technique, Histological,Techniques, Histological
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013194 Staining and Labeling The marking of biological material with a dye or other reagent for the purpose of identifying and quantitating components of tissues, cells or their extracts. Histological Labeling,Staining,Histological Labelings,Labeling and Staining,Labeling, Histological,Labelings, Histological,Stainings
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

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