-transparent.png){kind=logo}
Cardenolides from the bark of Calotropis gigantea. 2014
Pham Van Khang, and
Zhong-Guo Zhang, and
Yu-Hui Meng, and
De-An Guo, and
Xuan Liu, and
Li-Hong Hu, and
Lei Ma
a Shanghai Key Laboratory of New Drug Design , School of Pharmacy, East China University of Science and Technology , 130 Meilong Road, Shanghai 200237 , P.R. China.
Three new cardenolides (1-3) were isolated from the 90% ethanolic extract of the bark of a wild-type Calotropis gigantea. Their structures were determined by using NMR spectra and LC-MS analysis. Their inhibitory activities were evaluated against non-small cell lung carcinoma (A549) and human cervix epithelial adenocarcinoma (HeLa) cell lines. Compounds 1 and 3 exhibited strong inhibitory effect on two cancer cell lines.
Related Publications
Pham Van Khang, and
Zhong-Guo Zhang, and
Yu-Hui Meng, and
De-An Guo, and
Xuan Liu, and
Li-Hong Hu, and
Lei Ma
October 2013,
Steroids,
Pham Van Khang, and
Zhong-Guo Zhang, and
Yu-Hui Meng, and
De-An Guo, and
Xuan Liu, and
Li-Hong Hu, and
Lei Ma
December 2021,
Phytochemistry,
Pham Van Khang, and
Zhong-Guo Zhang, and
Yu-Hui Meng, and
De-An Guo, and
Xuan Liu, and
Li-Hong Hu, and
Lei Ma
May 2010,
Chemical & pharmaceutical bulletin,
Pham Van Khang, and
Zhong-Guo Zhang, and
Yu-Hui Meng, and
De-An Guo, and
Xuan Liu, and
Li-Hong Hu, and
Lei Ma
August 2006,
Journal of natural products,
Pham Van Khang, and
Zhong-Guo Zhang, and
Yu-Hui Meng, and
De-An Guo, and
Xuan Liu, and
Li-Hong Hu, and
Lei Ma
February 2020,
Journal of natural products,
Pham Van Khang, and
Zhong-Guo Zhang, and
Yu-Hui Meng, and
De-An Guo, and
Xuan Liu, and
Li-Hong Hu, and
Lei Ma
April 2021,
Bioorganic chemistry,
Pham Van Khang, and
Zhong-Guo Zhang, and
Yu-Hui Meng, and
De-An Guo, and
Xuan Liu, and
Li-Hong Hu, and
Lei Ma
July 2020,
Journal of natural products,
Pham Van Khang, and
Zhong-Guo Zhang, and
Yu-Hui Meng, and
De-An Guo, and
Xuan Liu, and
Li-Hong Hu, and
Lei Ma
December 2016,
Journal of ethnopharmacology,
Pham Van Khang, and
Zhong-Guo Zhang, and
Yu-Hui Meng, and
De-An Guo, and
Xuan Liu, and
Li-Hong Hu, and
Lei Ma
August 2009,
Journal of ethnopharmacology,
Pham Van Khang, and
Zhong-Guo Zhang, and
Yu-Hui Meng, and
De-An Guo, and
Xuan Liu, and
Li-Hong Hu, and
Lei Ma
June 2016,
Wilderness & environmental medicine,
