The effect of arsenic on some antioxidant enzyme activities and lipid peroxidation in various tissues of mirror carp (Cyprinus carpio carpio). 2015

Sayit Altikat, and Kazim Uysal, and Halil Isa Kuru, and Mustafa Kavasoglu, and Gul Nihan Ozturk, and Aysegul Kucuk
Department of Biochemistry, Faculty of Medicine, Dumlupınar University, Kutahya, Turkey, saitaltikat@hotmail.com.

The effect of arsenic bioaccumulation in liver, kidney, skin, muscle, and intestinal tissues of mirror carp (Cyprinus carpio carpio) was investigated on lipid peroxidation and certain antioxidant enzyme activities. In this study, three aquarium groups were formed from mirror carp: control group, 0.5-, and 1-mg/L arsenic concentrations. The fish were dissected after 1 month. Arsenic bioaccumulation, malondialdehyde (MDA) levels, catalase (CAT), and superoxide dismutase (SOD) enzyme activities were determined in the tissues. Results showed that arsenic was accumulated in liver, kidney, muscle, skin, and intestinal tissues. As the final product of lipid peroxidation, MDA levels were determined to have increased in all tissues with the exception of muscle. On the other hand, CAT and SOD enzyme activities in the fish tissues were decreased as compared to the control group. In the muscle tissue, differences were observed in the enzyme activities depending on arsenic concentration. Considering the increases in enzyme inhibition and MDA levels, liver was observed to be the main tissue affected in response to the arsenic toxicity.

UI MeSH Term Description Entries
D007413 Intestinal Mucosa Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI. Intestinal Epithelium,Intestinal Glands,Epithelium, Intestinal,Gland, Intestinal,Glands, Intestinal,Intestinal Gland,Mucosa, Intestinal
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D008315 Malondialdehyde The dialdehyde of malonic acid. Malonaldehyde,Propanedial,Malonylaldehyde,Malonyldialdehyde,Sodium Malondialdehyde,Malondialdehyde, Sodium
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D002347 Carps Common name for a number of different species of fish in the family Cyprinidae. This includes, among others, the common carp, crucian carp, grass carp, and silver carp. Carassius carassius,Crucian Carp,Cyprinus,Grass Carp,Carp,Ctenopharyngodon idellus,Cyprinus carpio,Hypophthalmichthys molitrix,Koi Carp,Silver Carp,Carp, Crucian,Carp, Grass,Carp, Koi,Carp, Silver,Carps, Crucian,Carps, Grass,Carps, Silver,Crucian Carps,Grass Carps,Silver Carps
D002374 Catalase An oxidoreductase that catalyzes the conversion of HYDROGEN PEROXIDE to water and oxygen. It is present in many animal cells. A deficiency of this enzyme results in ACATALASIA. Catalase A,Catalase T,Manganese Catalase,Mn Catalase
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001151 Arsenic A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed) Arsenic-75,Arsenic 75
D012867 Skin The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.

Related Publications

Sayit Altikat, and Kazim Uysal, and Halil Isa Kuru, and Mustafa Kavasoglu, and Gul Nihan Ozturk, and Aysegul Kucuk
January 1988, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology,
Sayit Altikat, and Kazim Uysal, and Halil Isa Kuru, and Mustafa Kavasoglu, and Gul Nihan Ozturk, and Aysegul Kucuk
November 2009, Reproductive biology,
Sayit Altikat, and Kazim Uysal, and Halil Isa Kuru, and Mustafa Kavasoglu, and Gul Nihan Ozturk, and Aysegul Kucuk
May 1990, Environmental monitoring and assessment,
Sayit Altikat, and Kazim Uysal, and Halil Isa Kuru, and Mustafa Kavasoglu, and Gul Nihan Ozturk, and Aysegul Kucuk
November 2001, Bulletin of environmental contamination and toxicology,
Sayit Altikat, and Kazim Uysal, and Halil Isa Kuru, and Mustafa Kavasoglu, and Gul Nihan Ozturk, and Aysegul Kucuk
April 2014, Diseases of aquatic organisms,
Sayit Altikat, and Kazim Uysal, and Halil Isa Kuru, and Mustafa Kavasoglu, and Gul Nihan Ozturk, and Aysegul Kucuk
January 2016, Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis,
Sayit Altikat, and Kazim Uysal, and Halil Isa Kuru, and Mustafa Kavasoglu, and Gul Nihan Ozturk, and Aysegul Kucuk
January 2019, PloS one,
Sayit Altikat, and Kazim Uysal, and Halil Isa Kuru, and Mustafa Kavasoglu, and Gul Nihan Ozturk, and Aysegul Kucuk
February 2016, Mitochondrial DNA. Part B, Resources,
Sayit Altikat, and Kazim Uysal, and Halil Isa Kuru, and Mustafa Kavasoglu, and Gul Nihan Ozturk, and Aysegul Kucuk
September 1995, The international journal of biochemistry & cell biology,
Sayit Altikat, and Kazim Uysal, and Halil Isa Kuru, and Mustafa Kavasoglu, and Gul Nihan Ozturk, and Aysegul Kucuk
January 1963, Comptes rendus des seances de la Societe de biologie et de ses filiales,
Copied contents to your clipboard!