| D007473 |
Ion Channels |
Gated, ion-selective glycoproteins that traverse membranes. The stimulus for ION CHANNEL GATING can be due to a variety of stimuli such as LIGANDS, a TRANSMEMBRANE POTENTIAL DIFFERENCE, mechanical deformation or through INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS. |
Membrane Channels,Ion Channel,Ionic Channel,Ionic Channels,Membrane Channel,Channel, Ion,Channel, Ionic,Channel, Membrane,Channels, Ion,Channels, Ionic,Channels, Membrane |
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| D009369 |
Neoplasms |
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. |
Benign Neoplasm,Cancer,Malignant Neoplasm,Tumor,Tumors,Benign Neoplasms,Malignancy,Malignant Neoplasms,Neoplasia,Neoplasm,Neoplasms, Benign,Cancers,Malignancies,Neoplasias,Neoplasm, Benign,Neoplasm, Malignant,Neoplasms, Malignant |
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| D009765 |
Obesity |
A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). |
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| D002001 |
Adipose Tissue, Brown |
A thermogenic form of adipose tissue composed of BROWN ADIPOCYTES. It is found in newborns of many species including humans, and in hibernating mammals. Brown fat is richly vascularized, innervated, and densely packed with MITOCHONDRIA which can generate heat directly from the stored lipids. |
Brown Fat,Hibernating Gland,Brown Adipose Tissue,Fat, Brown,Tissue, Brown Adipose |
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| D004734 |
Energy Metabolism |
The chemical reactions involved in the production and utilization of various forms of energy in cells. |
Bioenergetics,Energy Expenditure,Bioenergetic,Energy Expenditures,Energy Metabolisms,Expenditure, Energy,Expenditures, Energy,Metabolism, Energy,Metabolisms, Energy |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D000071256 |
Uncoupling Protein 1 |
A mitochondrial uncoupling protein that is expressed in BROWN ADIPOSE TISSUE. It is critical for NONSHIVERING THERMOGENESIS to prevent heat loss in NEONATES. |
BAT Uncoupling Protein,Brown Adipose Tissue Uncoupling Protein,Mitochondrial Brown Fat Uncoupling Protein 1,Mitochondrial Uncoupling Protein,SLC25A7 Protein,Solute Carrier Family 25 Member 7,Thermogenin,UCP1 Protein,Uncoupling Protein 1a,Uncoupling Protein, Mitochondrial Membrane,Uncoupling Protein, BAT,Uncoupling Protein, Mitochondrial |
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| D022722 |
Thermogenesis |
The generation of heat in order to maintain body temperature. The uncoupled oxidation of fatty acids contained within brown adipose tissue and SHIVERING are examples of thermogenesis in MAMMALS. |
Heat Production,Adaptive Thermogenesis,Facultative Thermogenesis,Nonshivering Thermogenesis,Production, Heat,Thermogeneses,Thermogenesis, Adaptive,Thermogenesis, Facultative,Thermogenesis, Nonshivering |
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| D024101 |
Mitochondrial Proteins |
Proteins encoded by the mitochondrial genome or proteins encoded by the nuclear genome that are imported to and resident in the MITOCHONDRIA. |
Proteins, Mitochondrial,Mitochondrial Protein,Protein, Mitochondrial |
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