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Antiarrhythmic effect of cordaron in patients with unstable stenocardia (34) and transmural myocardial infarction (39) has been studied in various dose regimens. A dose of 400-600 mg/day was significantly effective in unstable angina pectoris, while in myocardial infarction a 600 mg/day dose failed to attenuate arrhythmia, i.e. the number and frequency of extra-systoles reduced insignificantly. In subacute disease a 200 mg/day cordaron could not prevent an increment of arrhythmia showing inadequacy of a standard scheme of the drug administration.
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