[Determination of soluble complexes of fibrin monomers in plasma taking into consideration the fibrinogen level]. 1989

E P Ivanov, and D G Tsvirko, and V E Ivanov

Quantitative modifications of beta-naphthol, ethanol, and protamine sulfate tests are described, which are based on spectrophotometry of the formed precipitate. The findings have demonstrated a correlation between these tests' results and the plasma fibrinogen concentration. It is recommended that the paracoagulation test parameters be estimated with consideration for fibrinogen level. The results of measurements of the plasma fibrin monomer soluble complexes in 13 donors and in 72 patients with blood diseases and hemostasis are presented. The results permit a conclusion that these tests used alone or in various combinations are sufficiently sensitive, specific, and informative for the examinations of patients with disseminated intravascular coagulation; combined use of three paracoagulation tests has been found to be optimal.

UI MeSH Term Description Entries
D001780 Blood Coagulation Tests Laboratory tests for evaluating the individual's clotting mechanism. Coagulation Tests, Blood,Tests, Blood Coagulation,Blood Coagulation Test,Coagulation Test, Blood,Test, Blood Coagulation
D005338 Fibrin Fibrinogen Degradation Products Soluble protein fragments formed by the proteolytic action of plasmin on fibrin or fibrinogen. FDP and their complexes profoundly impair the hemostatic process and are a major cause of hemorrhage in intravascular coagulation and fibrinolysis. Antithrombin VI,Fibrin Degradation Product,Fibrin Degradation Products,Fibrin Fibrinogen Split Products,Degradation Product, Fibrin,Degradation Products, Fibrin,Product, Fibrin Degradation
D006402 Hematologic Diseases Disorders of the blood and blood forming tissues. Blood Diseases,Hematological Diseases,Blood Disease,Disease, Blood,Disease, Hematologic,Disease, Hematological,Diseases, Blood,Diseases, Hematologic,Diseases, Hematological,Hematologic Disease,Hematological Disease
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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