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In 16 healthy males bioavailability of Mexicord (Polfa) was studied, in comparison with mexiletine of foreign made. Bioavailability extent (EBA) of Mexicord was over 99% in comparison with a standard drug. Comparative study of antiarrhythmic activity and side effects was performed in 32 patients with frequent ventricular premalure beats and nearly in a half of them resistant to antiarrhythmic agents. Mexicord was effective in 47% of treated patients, and side effects (most often nausea) were observed in 28% of patients, but only in 1 case therapy withdrawal was necessary. Statistical study proved a lack of significant differences in antiarrhythmic effectiveness and side effects between Mexicord (Polfa) and a drug of foreign made.
Z Sadowski, and
D Paczkowski, and
M Markiewicz, and
E Nartowicz, and
P Koliński, and
M Filipek
January 1990,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
Z Sadowski, and
D Paczkowski, and
M Markiewicz, and
E Nartowicz, and
P Koliński, and
M Filipek
January 1990,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
Z Sadowski, and
D Paczkowski, and
M Markiewicz, and
E Nartowicz, and
P Koliński, and
M Filipek
November 1982,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
Z Sadowski, and
D Paczkowski, and
M Markiewicz, and
E Nartowicz, and
P Koliński, and
M Filipek
August 1987,
Zeitschrift fur Kardiologie,
Z Sadowski, and
D Paczkowski, and
M Markiewicz, and
E Nartowicz, and
P Koliński, and
M Filipek
January 1986,
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR,
Z Sadowski, and
D Paczkowski, and
M Markiewicz, and
E Nartowicz, and
P Koliński, and
M Filipek
November 1981,
Minerva cardioangiologica,
Z Sadowski, and
D Paczkowski, and
M Markiewicz, and
E Nartowicz, and
P Koliński, and
M Filipek
November 1985,
Nihon rinsho. Japanese journal of clinical medicine,
Z Sadowski, and
D Paczkowski, and
M Markiewicz, and
E Nartowicz, and
P Koliński, and
M Filipek
June 1986,
Kardiologiia,
Z Sadowski, and
D Paczkowski, and
M Markiewicz, and
E Nartowicz, and
P Koliński, and
M Filipek
January 1980,
Bollettino della Societa italiana di cardiologia,
Z Sadowski, and
D Paczkowski, and
M Markiewicz, and
E Nartowicz, and
P Koliński, and
M Filipek
February 1986,
Bratislavske lekarske listy,
