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Neuronal oscillations reflect the activity of neuronal ensembles engaged in integrative cognition, and may serve as a functional measure for the cognitive impairment in schizophrenia. This study aims to reveal the abnormal amplitude dynamics of electroencephalogram (EEG) oscillations in schizophrenia patients on multiple time scales. EEGs were recorded from schizophrenia patients ( n = 19) and healthy controls ( n = 16) while they were at resting state with eyes closed, at resting state with eyes open, and at watching video. Detrended fluctuation analysis and measures of life-time and waiting-time were used to characterize the abnormal dynamics of EEG oscillations on both long (1-20 s) and short (≤1 s) time scales. Abnormal dynamics of EEG oscillations in alpha and beta bands were observed. In particular, compared with healthy controls, schizophrenia patients have smaller DFA exponent (implying weaker long-range temporal correlation) in the left fronto-temporal area and smaller DFA exponent, smaller life-time (indicating shorter oscillation burst), and smaller waiting-time in the occipital area in beta band at resting state with eyes open. In addition, schizophrenia patients have larger DFA exponent, larger life-time, and larger waiting-time at some clustered channels in the temporo-parietal area in alpha band at watching video. The present results provide new insights for cognitive deficits and the underlying neuronal dysfunction in schizophrenia.
Junfeng Sun, and
Yingying Tang, and
Kelvin O Lim, and
Jijun Wang, and
Shanbao Tong, and
Hui Li, and
Bin He
April 2008,
Proceedings of the National Academy of Sciences of the United States of America,
Junfeng Sun, and
Yingying Tang, and
Kelvin O Lim, and
Jijun Wang, and
Shanbao Tong, and
Hui Li, and
Bin He
August 2019,
The Journal of physiology,
Junfeng Sun, and
Yingying Tang, and
Kelvin O Lim, and
Jijun Wang, and
Shanbao Tong, and
Hui Li, and
Bin He
June 2023,
Cognitive neurodynamics,
Junfeng Sun, and
Yingying Tang, and
Kelvin O Lim, and
Jijun Wang, and
Shanbao Tong, and
Hui Li, and
Bin He
June 2008,
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
Junfeng Sun, and
Yingying Tang, and
Kelvin O Lim, and
Jijun Wang, and
Shanbao Tong, and
Hui Li, and
Bin He
February 2010,
Nature reviews. Neuroscience,
Junfeng Sun, and
Yingying Tang, and
Kelvin O Lim, and
Jijun Wang, and
Shanbao Tong, and
Hui Li, and
Bin He
December 1996,
Biochemistry,
Junfeng Sun, and
Yingying Tang, and
Kelvin O Lim, and
Jijun Wang, and
Shanbao Tong, and
Hui Li, and
Bin He
April 2021,
Entropy (Basel, Switzerland),
Junfeng Sun, and
Yingying Tang, and
Kelvin O Lim, and
Jijun Wang, and
Shanbao Tong, and
Hui Li, and
Bin He
April 2004,
Motor control,
Junfeng Sun, and
Yingying Tang, and
Kelvin O Lim, and
Jijun Wang, and
Shanbao Tong, and
Hui Li, and
Bin He
July 2012,
Philosophical transactions of the Royal Society of London. Series B, Biological sciences,
Junfeng Sun, and
Yingying Tang, and
Kelvin O Lim, and
Jijun Wang, and
Shanbao Tong, and
Hui Li, and
Bin He
June 2009,
Physical review. E, Statistical, nonlinear, and soft matter physics,
