[Application fluorescein angiography: a new method for assessment of anterior eye segment hemomicrocirculation]. 2014

A V Petraevskiĭ, and I A Gndoian

OBJECTIVE To develop a noninvasive fluorescein angiography (FAG) method for the anterior eye segment (AES) assessment which would imply using the most-ordered site of bulbar conjunctival capillary bed as the object of dye administration. METHODS The study enrolled 30 individuals (41 eyes) with no evident ocular pathology and significant systemic diseases aged from 18 to 70 years and 19 patients with uveitis, of whom 10 patients (10 eyes) aged 43-57 had anterior uveitis and 9 patients (10 eyes) aged 17-29 had pars planitis. Assessment of conjunctival microcirculation was done by the proposed method of fluorescein angiography in which the dye is applied to the bulbar conjunctival capillary bed. RESULTS In all cases after a microdose of fluorescein was administered to the intermediate zone capillaries it distributed into two venous systems of the AES: peripheral and prelimbal venules. Circulation time and vascular permeability (depending on the presence or absence of extravasal hyperfluorescence) were described. Angiographic patterns in healthy individuals and patients with either clinical form of uveitis appeared to differ considerably. CONCLUSIONS Findings of the proposed noninvasive application FAG reflect the state of capillary and venular components of bulbar conjunctival microcirculatory system. Sings of increased hemoperfusion of the AES and vascular permeability were seen in patients with acute anterior uveitis, whereas in pars planitis patients vascular hyperpermeability was associated with decreased hemoperfusion of the AES. The proposed method can be used for monitoring of the inflammatory process in anterior and peripheral uveitis.

UI MeSH Term Description Entries
D008297 Male Males
D008833 Microcirculation The circulation of the BLOOD through the MICROVASCULAR NETWORK. Microvascular Blood Flow,Microvascular Circulation,Blood Flow, Microvascular,Circulation, Microvascular,Flow, Microvascular Blood,Microvascular Blood Flows,Microvascular Circulations
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D003228 Conjunctiva The mucous membrane that covers the posterior surface of the eyelids and the anterior pericorneal surface of the eyeball. Bulbar Conjunctiva,Palpebral Conjunctiva,Plica Semilunaris of Conjunctiva,Plicae Semilunares of Conjunctiva,Tunica Conjunctiva,Conjunctiva, Bulbar,Conjunctiva, Palpebral,Conjunctivas
D005260 Female Females
D005451 Fluorescein Angiography Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature. Fluorescence Angiography,Fundus Fluorescence Photography,Angiography, Fluorescein,Angiography, Fluorescence,Fluorescence Photography, Fundus,Photography, Fundus Fluorescence
D006464 Hemoperfusion Removal of toxins or metabolites from the circulation by the passing of blood, within a suitable extracorporeal circuit, over semipermeable microcapsules containing adsorbents (e.g., activated charcoal) or enzymes, other enzyme preparations (e.g., gel-entrapped microsomes, membrane-free enzymes bound to artificial carriers), or other adsorbents (e.g., various resins, albumin-conjugated agarose). Hemosorption,Hemoperfusions,Hemosorptions
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

A V Petraevskiĭ, and I A Gndoian
March 1975, The Journal of physiology,
A V Petraevskiĭ, and I A Gndoian
December 1971, Archives d'ophtalmologie et revue generale d'ophtalmologie,
A V Petraevskiĭ, and I A Gndoian
November 1971, Archives d'ophtalmologie et revue generale d'ophtalmologie,
A V Petraevskiĭ, and I A Gndoian
December 1988, Klinika oczna,
A V Petraevskiĭ, and I A Gndoian
August 1971, Annales d'oculistique,
A V Petraevskiĭ, and I A Gndoian
January 1976, International ophthalmology clinics,
A V Petraevskiĭ, and I A Gndoian
January 1976, Klinische Monatsblatter fur Augenheilkunde,
A V Petraevskiĭ, and I A Gndoian
December 1997, Acta ophthalmologica Scandinavica,
A V Petraevskiĭ, and I A Gndoian
May 1971, Annales d'oculistique,
A V Petraevskiĭ, and I A Gndoian
January 1991, Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,
Copied contents to your clipboard!