Biomaterial Database

Pathogenic and carcinogenic properties of silicon carbide. 1989

B Cichy

The article presents the influence of silicon carbide upon an organism, on the basis of the publications which, according to Chemical Abstracts, appeared on this subject from 1944 until 1987. The insolubility of silicon carbide, in the liquids of an organism and its indigestibility are indicated. A connection is presented between the size and shape of micrograins and the probability of tumor formation in rats; and the difference between silicon carbide and other dusts in the absorption of x-rays, inhibition of the TTC-dehydrogenase activity, collagenisation of lesions, carcinogenicity are also presented. The problem of interpretation of radiological images of lungs in people exposed to the influence of carborundum dust is dealt with. The biological inertness of silicon carbide is questioned.

UI	MeSH Term	Description	Entries
D008171	Lung Diseases	Pathological processes involving any part of the LUNG.	Pulmonary Diseases,Disease, Pulmonary,Diseases, Pulmonary,Pulmonary Disease,Disease, Lung,Diseases, Lung,Lung Disease
D009369	Neoplasms	New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	Benign Neoplasm,Cancer,Malignant Neoplasm,Tumor,Tumors,Benign Neoplasms,Malignancy,Malignant Neoplasms,Neoplasia,Neoplasm,Neoplasms, Benign,Cancers,Malignancies,Neoplasias,Neoplasm, Benign,Neoplasm, Malignant,Neoplasms, Malignant
D009374	Neoplasms, Experimental	Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms.	Experimental Neoplasms,Experimental Neoplasm,Neoplasm, Experimental
D009784	Occupational Diseases	Diseases caused by factors involved in one's employment.	Diseases, Occupational,Occupational Illnesses,Disease, Occupational,Illnesse, Occupational,Illnesses, Occupational,Occupational Disease,Occupational Illnesse
D002244	Carbon	A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.	Carbon-12,Vitreous Carbon,Carbon 12,Carbon, Vitreous
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012825	Silicon	A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].	Silicon-28,Silicon 28
D017554	Carbon Compounds, Inorganic	Inorganic compounds that contain carbon as an integral part of the molecule but are not derived from hydrocarbons.	Inorganic Carbon Compounds,Compounds, Inorganic Carbon
D017655	Silicon Compounds	Inorganic compounds that contain silicon as an integral part of the molecule.	Compounds, Silicon