Biomaterial Database

Iridocorneal endothelial syndrome. 2014

Adnan Aslam Saleem, and Mahmood Ali, and Farah Akhtar

Department of Ophthalmology, Al-Shifa Trust Eye Hospital, Rawalpindi.

A 19 years boy with a 2 years history of reduced and fluctuating vision along with change in pupillary shape and iris colour in his left eye presented to the glaucoma clinic. Ocular examination revealed distinct unilateral stretch holes, iris architecture changes and localized iris atrophy. Intraocular pressure was 16 mmHg in the right and 36 mmHg in the left eye. Gonioscopy of the left angle revealed broad based peripheral anterior synechiae at approximately 2 O'clock to 10 O'clock hours. The optic disc of the left eye had a vertical cup of 0.9 which manifest as superior and inferior arcuate scotoma. Specular microscopy showed unilateral abnormal endothelium with irregular cells of variable shape and size. To our knowledge, this is only the second reported case of iridocorneal endothelial syndrome in a male teenager.

UI	MeSH Term	Description	Entries
D007429	Intraocular Pressure	The pressure of the fluids in the eye.	Ocular Tension,Intraocular Pressures,Ocular Tensions,Pressure, Intraocular,Pressures, Intraocular,Tension, Ocular,Tensions, Ocular
D008297	Male		Males
D005472	Fluorouracil	A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.	5-FU,5-FU Lederle,5-FU Medac,5-Fluorouracil,5-Fluorouracil-Biosyn,5-HU Hexal,5FU,Adrucil,Carac,Efudex,Efudix,Fluoro-Uracile ICN,Fluoroplex,Fluorouracil Mononitrate,Fluorouracil Monopotassium Salt,Fluorouracil Monosodium Salt,Fluorouracil Potassium Salt,Fluorouracil-GRY,Fluorouracile Dakota,Fluorouracilo Ferrer Far,Fluoruracil,Fluracedyl,Flurodex,Haemato-FU,Neofluor,Onkofluor,Ribofluor,5 FU Lederle,5 FU Medac,5 Fluorouracil,5 Fluorouracil Biosyn,5 HU Hexal,Dakota, Fluorouracile,Fluoro Uracile ICN,Fluorouracil GRY,Haemato FU
D005901	Glaucoma	An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)	Glaucomas
D006068	Gonioscopy	Examination of the angle of the anterior chamber of the eye with a specialized optical instrument (gonioscope) or a contact prism lens.	Gonioscopies
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D014130	Trabeculectomy	Any surgical procedure for treatment of glaucoma by means of puncture or reshaping of the trabecular meshwork. It includes goniotomy, trabeculectomy, and laser perforation.	Goniotomy,Trabeculoplasty,Trabeculotomy,Goniotomies,Trabeculectomies,Trabeculoplasties,Trabeculotomies
D015812	Glaucoma, Angle-Closure	A form of glaucoma in which the intraocular pressure increases because the angle of the anterior chamber is blocked and the aqueous humor cannot drain from the anterior chamber.	Glaucoma, Closed-Angle,Glaucoma, Angle Closure,Glaucoma, Narrow-Angle,Glaucoma, Uncompensated,Glaucoma, Uncompensative,Angle Closure Glaucoma,Angle Closure Glaucomas,Angle-Closure Glaucoma,Angle-Closure Glaucomas,Closed-Angle Glaucoma,Closed-Angle Glaucomas,Glaucoma, Closed Angle,Glaucoma, Narrow Angle,Glaucomas, Angle Closure,Glaucomas, Angle-Closure,Glaucomas, Closed-Angle,Glaucomas, Narrow-Angle,Glaucomas, Uncompensated,Glaucomas, Uncompensative,Narrow-Angle Glaucoma,Narrow-Angle Glaucomas,Uncompensated Glaucoma,Uncompensated Glaucomas,Uncompensative Glaucoma,Uncompensative Glaucomas
D016896	Treatment Outcome	Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.	Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes